Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969189917> ?p ?o ?g. }
- W2969189917 abstract "Abstract Polarized protein distributions at the cortex play an important role in the spatial organization of cells. In S. pombe , growing microtubule ends contribute to the establishment and maintenance of such distributions by delivering specific factors to membrane receptors at the poles of the cell. It is however unclear how microtubule plus-end tracking of proteins favours protein accumulation at the cell cortex compared to proteins arriving directly from the cytoplasm. To address this question, we developed an in vitro assay, where microtubules were made to deliver His-tagged plus-end tracking proteins to functionalized microchamber walls. We found that motor-mediated protein clusters formed at microtubule ends were able to transfer to the walls, but non-clustered proteins were not. We further show that this transfer mechanism leads to preferential cluster accumulation at chamber poles, when microtubules are confined to elongated microfabricated chambers with sizes and shapes similar to S. pombe ." @default.
- W2969189917 created "2019-08-22" @default.
- W2969189917 creator A5011932505 @default.
- W2969189917 creator A5075606267 @default.
- W2969189917 date "2019-08-15" @default.
- W2969189917 modified "2023-09-27" @default.
- W2969189917 title "Motor-mediated clustering at microtubule plus ends facilitates protein transfer to a bio-mimetic cortex" @default.
- W2969189917 cites W1785817244 @default.
- W2969189917 cites W1803436399 @default.
- W2969189917 cites W1854281301 @default.
- W2969189917 cites W1965404941 @default.
- W2969189917 cites W1968714775 @default.
- W2969189917 cites W1970611771 @default.
- W2969189917 cites W1980086614 @default.
- W2969189917 cites W1985249910 @default.
- W2969189917 cites W1985501881 @default.
- W2969189917 cites W1996186152 @default.
- W2969189917 cites W1997691870 @default.
- W2969189917 cites W2013447580 @default.
- W2969189917 cites W2015005644 @default.
- W2969189917 cites W2018650334 @default.
- W2969189917 cites W2020838435 @default.
- W2969189917 cites W2022681444 @default.
- W2969189917 cites W2022943167 @default.
- W2969189917 cites W2027382153 @default.
- W2969189917 cites W2041841402 @default.
- W2969189917 cites W2042166633 @default.
- W2969189917 cites W2044820159 @default.
- W2969189917 cites W2058761402 @default.
- W2969189917 cites W2061135538 @default.
- W2969189917 cites W2074307550 @default.
- W2969189917 cites W2075725579 @default.
- W2969189917 cites W2082182602 @default.
- W2969189917 cites W2088001446 @default.
- W2969189917 cites W2088301401 @default.
- W2969189917 cites W2093998145 @default.
- W2969189917 cites W2098824895 @default.
- W2969189917 cites W2112591873 @default.
- W2969189917 cites W2123505394 @default.
- W2969189917 cites W2127334851 @default.
- W2969189917 cites W2128680169 @default.
- W2969189917 cites W2129158700 @default.
- W2969189917 cites W2129411210 @default.
- W2969189917 cites W2129997913 @default.
- W2969189917 cites W2138717221 @default.
- W2969189917 cites W2155485257 @default.
- W2969189917 cites W2157319245 @default.
- W2969189917 cites W2164700273 @default.
- W2969189917 cites W2171391648 @default.
- W2969189917 cites W221010953 @default.
- W2969189917 cites W2265061417 @default.
- W2969189917 cites W2288271511 @default.
- W2969189917 cites W2332446977 @default.
- W2969189917 cites W2436954922 @default.
- W2969189917 cites W2528687860 @default.
- W2969189917 cites W2560056367 @default.
- W2969189917 cites W2591669685 @default.
- W2969189917 cites W2606756014 @default.
- W2969189917 cites W2755149320 @default.
- W2969189917 cites W2889801491 @default.
- W2969189917 cites W2911769165 @default.
- W2969189917 doi "https://doi.org/10.1101/736728" @default.
- W2969189917 hasPublicationYear "2019" @default.
- W2969189917 type Work @default.
- W2969189917 sameAs 2969189917 @default.
- W2969189917 citedByCount "2" @default.
- W2969189917 countsByYear W29691899172021 @default.
- W2969189917 countsByYear W29691899172022 @default.
- W2969189917 crossrefType "posted-content" @default.
- W2969189917 hasAuthorship W2969189917A5011932505 @default.
- W2969189917 hasAuthorship W2969189917A5075606267 @default.
- W2969189917 hasBestOaLocation W29691899171 @default.
- W2969189917 hasConcept C12554922 @default.
- W2969189917 hasConcept C142669718 @default.
- W2969189917 hasConcept C1491633281 @default.
- W2969189917 hasConcept C169760540 @default.
- W2969189917 hasConcept C185592680 @default.
- W2969189917 hasConcept C190062978 @default.
- W2969189917 hasConcept C20418707 @default.
- W2969189917 hasConcept C204462481 @default.
- W2969189917 hasConcept C2777348757 @default.
- W2969189917 hasConcept C41625074 @default.
- W2969189917 hasConcept C55493867 @default.
- W2969189917 hasConcept C59006786 @default.
- W2969189917 hasConcept C84425145 @default.
- W2969189917 hasConcept C86803240 @default.
- W2969189917 hasConcept C93126451 @default.
- W2969189917 hasConcept C95444343 @default.
- W2969189917 hasConceptScore W2969189917C12554922 @default.
- W2969189917 hasConceptScore W2969189917C142669718 @default.
- W2969189917 hasConceptScore W2969189917C1491633281 @default.
- W2969189917 hasConceptScore W2969189917C169760540 @default.
- W2969189917 hasConceptScore W2969189917C185592680 @default.
- W2969189917 hasConceptScore W2969189917C190062978 @default.
- W2969189917 hasConceptScore W2969189917C20418707 @default.
- W2969189917 hasConceptScore W2969189917C204462481 @default.
- W2969189917 hasConceptScore W2969189917C2777348757 @default.
- W2969189917 hasConceptScore W2969189917C41625074 @default.
- W2969189917 hasConceptScore W2969189917C55493867 @default.
- W2969189917 hasConceptScore W2969189917C59006786 @default.