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- W2969253193 abstract "The present study aimed to prepare a combined inactivated vaccine containingbovine viral diarrhea genotype-1(BVD-1),bovine viral diarrhea genotype-2 (BVD-2),infectious bovine rhinotracheitis (IBR),parainfluenza-3 (PI-3) and bovinerespiratory syncytial virus(BRSV) and adjuvanted with montanide oil ISA 206.Quality control results proved that the pneumo-5 vaccine was pure and completelysafe to be used in calves without abnormalities. Potency test was performed ontwo groups of calves three for each group, where the first group was vaccinatedwith pneumo-5 vaccine adjuvant with montanide oil ISA 206 and the second groupwas left as non-vaccinated control group. In group (1), serum neutralization testrevealed that the serum neutralizing antibody titers in BVD-1 and BVD-2 developedmore higher than the minimal acceptable titer of the protective level (log10 0.9),while log10 0.6 was protective against IBR, PI-3 and BRS viruses at one month ofvaccination and remained protective till the end of experiment compared to group(2) that showed no neutralizing antibody response. The prepared vaccine provedto be highly potent as the developed BVD-1, BVD-2, IBR, PI-3 and BRSV antibodiesremained within the protective level for 9 months post vaccination." @default.
- W2969253193 created "2019-08-29" @default.
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- W2969253193 date "2017-06-01" @default.
- W2969253193 modified "2023-09-27" @default.
- W2969253193 title "Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves" @default.
- W2969253193 doi "https://doi.org/10.21608/jvmr.2017.43261" @default.
- W2969253193 hasPublicationYear "2017" @default.
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