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- W2969410117 abstract "A simple, sensitive, accurate and precise reverse phase high performance liquid chromatographic method has been developed for the simultaneous estimation of Valsartan and Cilnidipine. The purposed RP-HPLC method utilizes stationary phase and consists of symmetry C18 (250 × 4.6 mm, 5 μm in particle size) with a mobile phase comprising of Acetonitrile: Ammonium Acetate Buffer (75:25%v/v) pH 5.0 adjusted by Triethylamine at a flow rate of 1.0 mL/min, column temperature of 25 °C and UV detection at 240 nm. The retention time of Valsartan and Cilnidipine were 2.45 and 8.43 min respectively. The linearity was found to be in the range of 4–20 g/mL and 24–120 μg/mL for Cilnidipine and Valsartan respectively. The % recovery was found to be 100.06 ± 0.226 for Cilnidipine and 99.03 ± 0.3030 for Valsartan. The proposed method was validated as per ICH guidelines and successfully applied for the determination of drugs in tablet Keywords: Cilnidipine, Valsartan, simultaneous estimation, validation, RP-HPLC Cite this Article Bhole Ritesh P, Pawara Vinayak C, Chitlange Sohan S, et al. Development and validation of HPLC method for simultaneous estimation of Cilnidipine and Valsartan in bulk and tablet dosage form. Research & Reviews: A Journal of Pharmaceutical Science. 2015; 6(2): 28–36p." @default.
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- W2969410117 date "2019-07-11" @default.
- W2969410117 modified "2023-09-24" @default.
- W2969410117 title "Development and Validation of HPLC Method for Simultaneous Estimation of Cilnidipine and Valsartan in Bulk and Tablet Dosage Form" @default.
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