FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969474413> ?p ?o ?g. }

• W2969474413 endingPage "724" @default.
• W2969474413 startingPage "713" @default.
• W2969474413 abstract "Reductions in pneumonia hospitalisations following introduction of pneumococcal conjugate vaccines (PCVs) have been reported from high-incidence and low-incidence settings but long-term data comparing vaccinated with unvaccinated children are sparse.We did a retrospective, population-based, record-linkage cohort study in Australian children using administrative health data from the Western Australian Midwives' Notification System and New South Wales Perinatal Data Collection, and the birth and death registries in both states. PCV vaccination details, pneumonia-coded hospital admissions, and invasive pneumococcal disease notification records were individually linked for children born between 2001 and 2012. The primary outcome was defined as the first hospital admission for all-cause pneumonia. Cox models were used to calculate adjusted hazard ratios (HR) to estimate the effect of PCV doses on pneumonia-coded hospital admissions by Aboriginal status, birth period, remoteness, and pneumonia diagnostic category in children younger than 2 years. Person-time of follow-up time for each child started at birth and was censored at the earliest of first hospital admission for all-cause pneumonia, death, invalid PCV dose, when the child reached age 24 months, or the end date of the study period (Dec 31, 2013) FINDINGS: The study cohort comprised 1 365 893 children liveborn between Jan 1, 2001, and Dec 31, 2012, of whom 66 484 (4·9%) were identified as Aboriginal. The overall rate for all-cause pneumonia hospital admissions for children younger than 2 years over the entire study period was 17·6/1000 child-years in Aboriginal children and 5·5/1000 child-years in non-Aboriginal children. Compared with children born between 2001 and 2004 (ie, the pre-universal PCV period), the incidence of pneumonia-coded hospital admissions decreased in both vaccinated (6·5 vs 5·7 per 1000 child-years [12% reduction, 95% CI 3-21; p=0·01]) and unvaccinated non-Aboriginal children (6·8 vs 3·7 [45% reduction; 41-49]) born 2005-12 (the universal PCV period); among Aboriginal children, declines were significant only among those vaccinated (27·4 vs 14·1 [49% reduction, 40-55]). Among Aboriginal children born 2005-12, the risk of pneumonia-coded hospital admission after three doses of PCV was lower than those unvaccinated (adjusted HR 0·83, 95% CI 0·65-0·99) but, among non-Aboriginal children, the risk was similar (adjusted HR 1·09, 0·98-1·22). Overall, remote-born Aboriginal children had the highest incidence of hospital admission for pneumonia and among children born 2005-12, the adjusted risk was 37% lower (adjusted HR 0·63, 95% CI 0·42-0·96) among those fully vaccinated than those unvaccinated.Reductions in pneumonia-coded hospital admissions in unvaccinated children predominated in non-Aboriginal children with low incidence of pneumonia but were not significant in Aboriginal children with high incidence. These findings have potential implications for measuring PCV effect using a non-specific endpoint such as all-cause pneumonia in high-incidence populations.Commonwealth Government Collaborative Research Infrastructure Strategy and Education Investment Fund Super Science Initiative and the Australian National Health and Medical Research Council." @default.
• W2969474413 created "2019-08-29" @default.
• W2969474413 creator A5012521967 @default.
• W2969474413 creator A5016466948 @default.
• W2969474413 creator A5017585559 @default.
• W2969474413 creator A5045071155 @default.
• W2969474413 creator A5049164171 @default.
• W2969474413 creator A5054461236 @default.
• W2969474413 creator A5055156227 @default.
• W2969474413 creator A5075722318 @default.
• W2969474413 creator A5088980739 @default.
• W2969474413 date "2019-10-01" @default.
• W2969474413 modified "2023-09-26" @default.
• W2969474413 title "Effectiveness of pneumococcal conjugate vaccine against hospital admissions for pneumonia in Australian children: a retrospective, population-based, record-linked cohort study" @default.
• W2969474413 cites W1977198231 @default.
• W2969474413 cites W1983730400 @default.
• W2969474413 cites W1998572742 @default.
• W2969474413 cites W2003754310 @default.
• W2969474413 cites W2097188627 @default.
• W2969474413 cites W2103773696 @default.
• W2969474413 cites W2106502289 @default.
• W2969474413 cites W2121369371 @default.
• W2969474413 cites W2122598469 @default.
• W2969474413 cites W2129956327 @default.
• W2969474413 cites W2138482851 @default.
• W2969474413 cites W2149205577 @default.
• W2969474413 cites W2150562212 @default.
• W2969474413 cites W2151514808 @default.
• W2969474413 cites W2168282445 @default.
• W2969474413 cites W2168613507 @default.
• W2969474413 cites W2183027487 @default.
• W2969474413 cites W2274717124 @default.
• W2969474413 cites W2592582632 @default.
• W2969474413 cites W2606215982 @default.
• W2969474413 cites W2621893872 @default.
• W2969474413 cites W2754234471 @default.
• W2969474413 cites W2765150235 @default.
• W2969474413 cites W2795691478 @default.
• W2969474413 cites W2806835586 @default.
• W2969474413 cites W2888692583 @default.
• W2969474413 doi "https://doi.org/10.1016/s2352-4642(19)30249-4" @default.
• W2969474413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31439496" @default.
• W2969474413 hasPublicationYear "2019" @default.
• W2969474413 type Work @default.
• W2969474413 sameAs 2969474413 @default.
• W2969474413 citedByCount "12" @default.
• W2969474413 countsByYear W29694744132019 @default.
• W2969474413 countsByYear W29694744132020 @default.
• W2969474413 countsByYear W29694744132021 @default.
• W2969474413 countsByYear W29694744132022 @default.
• W2969474413 countsByYear W29694744132023 @default.
• W2969474413 crossrefType "journal-article" @default.
• W2969474413 hasAuthorship W2969474413A5012521967 @default.
• W2969474413 hasAuthorship W2969474413A5016466948 @default.
• W2969474413 hasAuthorship W2969474413A5017585559 @default.
• W2969474413 hasAuthorship W2969474413A5045071155 @default.
• W2969474413 hasAuthorship W2969474413A5049164171 @default.
• W2969474413 hasAuthorship W2969474413A5054461236 @default.
• W2969474413 hasAuthorship W2969474413A5055156227 @default.
• W2969474413 hasAuthorship W2969474413A5075722318 @default.
• W2969474413 hasAuthorship W2969474413A5088980739 @default.
• W2969474413 hasConcept C120665830 @default.
• W2969474413 hasConcept C121332964 @default.
• W2969474413 hasConcept C126322002 @default.
• W2969474413 hasConcept C142210648 @default.
• W2969474413 hasConcept C167135981 @default.
• W2969474413 hasConcept C187212893 @default.
• W2969474413 hasConcept C201903717 @default.
• W2969474413 hasConcept C207103383 @default.
• W2969474413 hasConcept C2777914695 @default.
• W2969474413 hasConcept C2778866548 @default.
• W2969474413 hasConcept C2781253189 @default.
• W2969474413 hasConcept C2908647359 @default.
• W2969474413 hasConcept C44249647 @default.
• W2969474413 hasConcept C523546767 @default.
• W2969474413 hasConcept C54355233 @default.
• W2969474413 hasConcept C61511704 @default.
• W2969474413 hasConcept C71924100 @default.
• W2969474413 hasConcept C72563966 @default.
• W2969474413 hasConcept C86803240 @default.
• W2969474413 hasConcept C88879693 @default.
• W2969474413 hasConcept C99454951 @default.
• W2969474413 hasConceptScore W2969474413C120665830 @default.
• W2969474413 hasConceptScore W2969474413C121332964 @default.
• W2969474413 hasConceptScore W2969474413C126322002 @default.
• W2969474413 hasConceptScore W2969474413C142210648 @default.
• W2969474413 hasConceptScore W2969474413C167135981 @default.
• W2969474413 hasConceptScore W2969474413C187212893 @default.
• W2969474413 hasConceptScore W2969474413C201903717 @default.
• W2969474413 hasConceptScore W2969474413C207103383 @default.
• W2969474413 hasConceptScore W2969474413C2777914695 @default.
• W2969474413 hasConceptScore W2969474413C2778866548 @default.
• W2969474413 hasConceptScore W2969474413C2781253189 @default.
• W2969474413 hasConceptScore W2969474413C2908647359 @default.
• W2969474413 hasConceptScore W2969474413C44249647 @default.
• W2969474413 hasConceptScore W2969474413C523546767 @default.
• W2969474413 hasConceptScore W2969474413C54355233 @default.
• W2969474413 hasConceptScore W2969474413C61511704 @default.

• next