FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969477592> ?p ?o ?g. }

• W2969477592 abstract "The aim of this study was to investigate the effects and mechanisms of ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7) on lung cancer cells.The expression characteristics of ENTPD7 and its effect on the survival of lung cancer patients were analyzed by referring to The Cancer Genome Atlas (TCGA). Streptavidin-peroxidase (SP) staining was performed to detect the ENTPD7 protein in tumor tissues and adjacent tissues. Plasmid transfection technology was also applied to silence ENTPD7 gene. Crystal violet staining and flow cytometry were performed to determine cell proliferation and apoptosis. Tumor-bearing nude mice model was established to investigate the effect of sh-ENTPD7 on tumors.The results showed that patients with low levels of ENTPD7 had higher survival rates. ENTPD7 was up-regulated in lung cancer tissues and cells. Down-regulation of the expression of ENTPD7 inhibited proliferation but promoted apoptosis of lung cancer cell. Silencing ENTPD7 also inhibited the expression levels of Ras and Raf proteins and the phosphorylation of mitogen-activated protein kinase (MEK) and extracellular signal-regulated kinase (ERK). Tumor-bearing nude mice experiments showed that silencing ENTPD7 had an inhibitory effect on lung cancer cells.ENTPD7 was overexpressed in lung cancer cells. Down-regulating ENTPD7 could inhibit lung cancer cell proliferation and promote apoptosis via inhibiting the Ras/Raf/MEK/ERK pathway." @default.
• W2969477592 created "2019-08-29" @default.
• W2969477592 creator A5036614819 @default.
• W2969477592 creator A5036845831 @default.
• W2969477592 creator A5043671209 @default.
• W2969477592 creator A5051647408 @default.
• W2969477592 creator A5066039252 @default.
• W2969477592 creator A5067134029 @default.
• W2969477592 creator A5089795992 @default.
• W2969477592 date "2019-08-23" @default.
• W2969477592 modified "2023-10-17" @default.
• W2969477592 title "Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7)" @default.
• W2969477592 cites W1442157793 @default.
• W2969477592 cites W1541216052 @default.
• W2969477592 cites W1583472519 @default.
• W2969477592 cites W1757407923 @default.
• W2969477592 cites W1902101558 @default.
• W2969477592 cites W1921840267 @default.
• W2969477592 cites W1970206879 @default.
• W2969477592 cites W1973496588 @default.
• W2969477592 cites W1980754306 @default.
• W2969477592 cites W1982146517 @default.
• W2969477592 cites W1982488143 @default.
• W2969477592 cites W1994577132 @default.
• W2969477592 cites W1997795769 @default.
• W2969477592 cites W2005961460 @default.
• W2969477592 cites W2010656553 @default.
• W2969477592 cites W2016086538 @default.
• W2969477592 cites W2021876472 @default.
• W2969477592 cites W2027931017 @default.
• W2969477592 cites W2034643457 @default.
• W2969477592 cites W2035369903 @default.
• W2969477592 cites W2042000503 @default.
• W2969477592 cites W2042307727 @default.
• W2969477592 cites W2045055958 @default.
• W2969477592 cites W2050013530 @default.
• W2969477592 cites W2054259191 @default.
• W2969477592 cites W2061619522 @default.
• W2969477592 cites W2062413213 @default.
• W2969477592 cites W2066649636 @default.
• W2969477592 cites W2080537230 @default.
• W2969477592 cites W2087988673 @default.
• W2969477592 cites W2090067193 @default.
• W2969477592 cites W2090146004 @default.
• W2969477592 cites W2095988220 @default.
• W2969477592 cites W2113586342 @default.
• W2969477592 cites W2118965542 @default.
• W2969477592 cites W2143422202 @default.
• W2969477592 cites W2152983030 @default.
• W2969477592 cites W2154140726 @default.
• W2969477592 cites W2160768469 @default.
• W2969477592 cites W2166521422 @default.
• W2969477592 cites W2168374849 @default.
• W2969477592 cites W2171565634 @default.
• W2969477592 cites W2195247392 @default.
• W2969477592 cites W2216220222 @default.
• W2969477592 cites W2310946193 @default.
• W2969477592 cites W2312180837 @default.
• W2969477592 cites W2520322757 @default.
• W2969477592 cites W2530620398 @default.
• W2969477592 cites W2542029354 @default.
• W2969477592 cites W2553383160 @default.
• W2969477592 cites W2560367415 @default.
• W2969477592 cites W2566123206 @default.
• W2969477592 cites W2572174216 @default.
• W2969477592 cites W2587862832 @default.
• W2969477592 cites W2785047426 @default.
• W2969477592 cites W3490365 @default.
• W2969477592 doi "https://doi.org/10.1186/s12931-019-1165-0" @default.
• W2969477592 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6708200" @default.
• W2969477592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31443651" @default.
• W2969477592 hasPublicationYear "2019" @default.
• W2969477592 type Work @default.
• W2969477592 sameAs 2969477592 @default.
• W2969477592 citedByCount "6" @default.
• W2969477592 countsByYear W29694775922020 @default.
• W2969477592 countsByYear W29694775922021 @default.
• W2969477592 countsByYear W29694775922022 @default.
• W2969477592 crossrefType "journal-article" @default.
• W2969477592 hasAuthorship W2969477592A5036614819 @default.
• W2969477592 hasAuthorship W2969477592A5036845831 @default.
• W2969477592 hasAuthorship W2969477592A5043671209 @default.
• W2969477592 hasAuthorship W2969477592A5051647408 @default.
• W2969477592 hasAuthorship W2969477592A5066039252 @default.
• W2969477592 hasAuthorship W2969477592A5067134029 @default.
• W2969477592 hasAuthorship W2969477592A5089795992 @default.
• W2969477592 hasBestOaLocation W29694775921 @default.
• W2969477592 hasConcept C104317684 @default.
• W2969477592 hasConcept C119056186 @default.
• W2969477592 hasConcept C121608353 @default.
• W2969477592 hasConcept C142724271 @default.
• W2969477592 hasConcept C153911025 @default.
• W2969477592 hasConcept C184235292 @default.
• W2969477592 hasConcept C190283241 @default.
• W2969477592 hasConcept C2776256026 @default.
• W2969477592 hasConcept C502942594 @default.
• W2969477592 hasConcept C54355233 @default.
• W2969477592 hasConcept C55493867 @default.
• W2969477592 hasConcept C57074206 @default.
• W2969477592 hasConcept C62112901 @default.

• next