FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969477789> ?p ?o ?g. }

• W2969477789 endingPage "549" @default.
• W2969477789 startingPage "543" @default.
• W2969477789 abstract "Context: HemoHIM is a medicinal herbal preparation of Angelica gigas Nakai (Apiaceae), Cnidium officinale Makino (Umbelliferae), and Paeonia japonica Miyabe (Paeoniaceae) developed for immune regulation. HemoHIM has been investigated for its ability to enhance tissue self-renewal and stimulate immune systems. To date, studies on the protective effects of HemoHIM against gastritis and gastric ulcers have not been conducted.Objective: The protective effects of HemoHIM using models of indomethacin and ethanol/hydrochloric acid (EtOH/HCl)-induced gastric mucosal injury were investigated.Materials and methods: Rats were divided into five groups (n = 10): control, indomethacin, or EtOH/HCl groups, HemoHIM 250, 500 mg kg−1, and cimetidine 100 mg kg−1, respectively. Indomethacin (80 mg kg−1) and 60% EtOH/150 mM HCl were administered orally 1 h after the administration of samples and rats were anesthetized 3 h after induction. The lesion area (%), inhibition ratio (%), and total acidity were investigated, and tissues were histopathologically analyzed using hematoxylin and-eosin (H&E) staining.Results: HemoHIM significantly reduced gastric injury in indomethacin-induced model (250 and 500 mg kg−1; 64.30% and 67.75%, p < 0.001) compared to indomethacin group. In the EtOH/HCl-induced model, HemoHIM reduced gastric lesion (250 and 500 mg kg−1; 61.05% and 73.37%, p < 0.001) and gastric acidity (250 and 500 mg kg−1; 37.80 and 45.20 meq L−1, p < 0.001) compared to EtOH/HCl group. H&E staining of the gastric mucosa showed decreased erosion and hemorrhage in HemoHIM group compared to EtOH/HCl group.Discussion and conclusions: Based on the results, HemoHIM is potential candidate for the treatment of gastritis and gastric ulcers." @default.
• W2969477789 created "2019-08-29" @default.
• W2969477789 creator A5000738817 @default.
• W2969477789 creator A5001668841 @default.
• W2969477789 creator A5016582329 @default.
• W2969477789 creator A5035789097 @default.
• W2969477789 creator A5042297321 @default.
• W2969477789 creator A5043217571 @default.
• W2969477789 creator A5050759059 @default.
• W2969477789 creator A5058775984 @default.
• W2969477789 creator A5058935068 @default.
• W2969477789 date "2019-01-01" @default.
• W2969477789 modified "2023-10-15" @default.
• W2969477789 title "Protective effects of a standardized extract (HemoHIM) using indomethacin- and ethanol/HCl-induced gastric mucosal injury models" @default.
• W2969477789 cites W1957398406 @default.
• W2969477789 cites W1965275500 @default.
• W2969477789 cites W1966172901 @default.
• W2969477789 cites W1974905994 @default.
• W2969477789 cites W1976162686 @default.
• W2969477789 cites W2031837541 @default.
• W2969477789 cites W2033353801 @default.
• W2969477789 cites W2035132638 @default.
• W2969477789 cites W2044909165 @default.
• W2969477789 cites W2079903475 @default.
• W2969477789 cites W2085035122 @default.
• W2969477789 cites W2091725641 @default.
• W2969477789 cites W2092062767 @default.
• W2969477789 cites W2096456854 @default.
• W2969477789 cites W2117219003 @default.
• W2969477789 cites W2159953327 @default.
• W2969477789 cites W2339396971 @default.
• W2969477789 cites W2416863842 @default.
• W2969477789 cites W2560011936 @default.
• W2969477789 cites W2604412079 @default.
• W2969477789 cites W260551304 @default.
• W2969477789 cites W2767749509 @default.
• W2969477789 cites W2783464254 @default.
• W2969477789 cites W2789780411 @default.
• W2969477789 cites W2802949901 @default.
• W2969477789 cites W2908003695 @default.
• W2969477789 cites W4290359723 @default.
• W2969477789 doi "https://doi.org/10.1080/13880209.2019.1651875" @default.
• W2969477789 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6713185" @default.
• W2969477789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31429615" @default.
• W2969477789 hasPublicationYear "2019" @default.
• W2969477789 type Work @default.
• W2969477789 sameAs 2969477789 @default.
• W2969477789 citedByCount "17" @default.
• W2969477789 countsByYear W29694777892020 @default.
• W2969477789 countsByYear W29694777892021 @default.
• W2969477789 countsByYear W29694777892022 @default.
• W2969477789 countsByYear W29694777892023 @default.
• W2969477789 crossrefType "journal-article" @default.
• W2969477789 hasAuthorship W2969477789A5000738817 @default.
• W2969477789 hasAuthorship W2969477789A5001668841 @default.
• W2969477789 hasAuthorship W2969477789A5016582329 @default.
• W2969477789 hasAuthorship W2969477789A5035789097 @default.
• W2969477789 hasAuthorship W2969477789A5042297321 @default.
• W2969477789 hasAuthorship W2969477789A5043217571 @default.
• W2969477789 hasAuthorship W2969477789A5050759059 @default.
• W2969477789 hasAuthorship W2969477789A5058775984 @default.
• W2969477789 hasAuthorship W2969477789A5058935068 @default.
• W2969477789 hasBestOaLocation W29694777891 @default.
• W2969477789 hasConcept C125473707 @default.
• W2969477789 hasConcept C142724271 @default.
• W2969477789 hasConcept C151730666 @default.
• W2969477789 hasConcept C185592680 @default.
• W2969477789 hasConcept C188947578 @default.
• W2969477789 hasConcept C204787440 @default.
• W2969477789 hasConcept C2779343474 @default.
• W2969477789 hasConcept C2779422922 @default.
• W2969477789 hasConcept C2779454681 @default.
• W2969477789 hasConcept C2780161600 @default.
• W2969477789 hasConcept C2780719153 @default.
• W2969477789 hasConcept C2781443798 @default.
• W2969477789 hasConcept C55493867 @default.
• W2969477789 hasConcept C556039675 @default.
• W2969477789 hasConcept C71924100 @default.
• W2969477789 hasConcept C74864618 @default.
• W2969477789 hasConcept C86803240 @default.
• W2969477789 hasConcept C98274493 @default.
• W2969477789 hasConceptScore W2969477789C125473707 @default.
• W2969477789 hasConceptScore W2969477789C142724271 @default.
• W2969477789 hasConceptScore W2969477789C151730666 @default.
• W2969477789 hasConceptScore W2969477789C185592680 @default.
• W2969477789 hasConceptScore W2969477789C188947578 @default.
• W2969477789 hasConceptScore W2969477789C204787440 @default.
• W2969477789 hasConceptScore W2969477789C2779343474 @default.
• W2969477789 hasConceptScore W2969477789C2779422922 @default.
• W2969477789 hasConceptScore W2969477789C2779454681 @default.
• W2969477789 hasConceptScore W2969477789C2780161600 @default.
• W2969477789 hasConceptScore W2969477789C2780719153 @default.
• W2969477789 hasConceptScore W2969477789C2781443798 @default.
• W2969477789 hasConceptScore W2969477789C55493867 @default.
• W2969477789 hasConceptScore W2969477789C556039675 @default.
• W2969477789 hasConceptScore W2969477789C71924100 @default.
• W2969477789 hasConceptScore W2969477789C74864618 @default.
• W2969477789 hasConceptScore W2969477789C86803240 @default.

• next