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• W2969483257 abstract "ABSTRACT Glycine receptors (GlyRs) are indispensable to maintain excitatory/inhibitory balance in neuronal circuits controlling reflex and rhythmic motor behaviors. Here we have developed Glyght, the first GlyR ligand controlled with light. It is selective over other cys-loop receptors, active in vivo , and displays an allosteric mechanism of action. The photomanipulation of glycinergic neurotransmission opens new avenues to understand inhibitory circuits in intact animals, and to develop drug-based phototherapies." @default.
• W2969483257 created "2019-08-29" @default.
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• W2969483257 date "2019-08-22" @default.
• W2969483257 modified "2023-10-06" @default.
• W2969483257 title "Photocontrol of endogenous glycine receptors in vivo" @default.
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• W2969483257 doi "https://doi.org/10.1101/744391" @default.
• W2969483257 hasPublicationYear "2019" @default.
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