Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969486566> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2969486566 abstract "AIM: to reduce antibiotic resistance of infectious agents in colorectal surgery using optimal antibiotic therapy. PATIENTS AND METHODS: single-center interventional study with retrospective control has been done. Start point of intervention was January 2017, when it was provided direct administrative control of perioperative antibiotic prophylaxis protocols and empirical antibiotic therapy. The study included 200 patients after colorectal surgery in 2016-2017. Patients divided in two groups: in 2016 y – control (A), in 2017 – interventional one (B). RESULTS: significant decrease was detected in total antibiotic use from 16.1 to 12.2 defined daily dose (DDD) and in duration of antibiotic prophylaxis from 5.5 to 1.9 days (p<0.001). Incidence of infection caused by multi-resistant strains reduced from 84.3% to 50% (p<0.001). Analysis of etiology septic complications in colorectal patients showed a decrease in the number of Enterobacteriales, producing extended-spectrum beta-lactamases (ESBL) from 33.3% to 11.8% (р<0.01). The incidence of carbapenem-resistant Klostridium pneumoniae reduced from 7.8% до 0%, р=0.031. ESKAPE group pathogens decreased from 24 (47.1%) to 12 (17.7%), р<0.001. No difference in postoperative infectious morbidity between groups was detected (32.9% vs 31.0%, р=0.88). Incidence of antibiotic-associated diarrhea decreased from 5% to 0% (р=0.03). CONCLUSION: direct control of antibiotic prophylaxis protocols and empirical antibiotic therapy allowed to decrease the rate of antibiotic use and to decrease rate of infection complications caused by antibiotic resistance strains." @default.
- W2969486566 created "2019-08-29" @default.
- W2969486566 creator A5031597111 @default.
- W2969486566 creator A5038370585 @default.
- W2969486566 creator A5044869795 @default.
- W2969486566 creator A5047111072 @default.
- W2969486566 creator A5069206869 @default.
- W2969486566 date "2019-08-23" @default.
- W2969486566 modified "2023-09-26" @default.
- W2969486566 title "SYSTEMS APPROACH FOR ANTIBIOTICS IN COLORECTAL SURGERY IN GROWING ANTIMICROBIAL RESISTANCE BACKGROUND" @default.
- W2969486566 cites W1824332292 @default.
- W2969486566 cites W2115486016 @default.
- W2969486566 cites W2944138215 @default.
- W2969486566 cites W3152226039 @default.
- W2969486566 doi "https://doi.org/10.33878/2073-7556-2019-18-3-49-54" @default.
- W2969486566 hasPublicationYear "2019" @default.
- W2969486566 type Work @default.
- W2969486566 sameAs 2969486566 @default.
- W2969486566 citedByCount "0" @default.
- W2969486566 crossrefType "journal-article" @default.
- W2969486566 hasAuthorship W2969486566A5031597111 @default.
- W2969486566 hasAuthorship W2969486566A5038370585 @default.
- W2969486566 hasAuthorship W2969486566A5044869795 @default.
- W2969486566 hasAuthorship W2969486566A5047111072 @default.
- W2969486566 hasAuthorship W2969486566A5069206869 @default.
- W2969486566 hasBestOaLocation W29694865661 @default.
- W2969486566 hasConcept C120665830 @default.
- W2969486566 hasConcept C121332964 @default.
- W2969486566 hasConcept C126322002 @default.
- W2969486566 hasConcept C137627325 @default.
- W2969486566 hasConcept C141071460 @default.
- W2969486566 hasConcept C167135981 @default.
- W2969486566 hasConcept C2778602436 @default.
- W2969486566 hasConcept C2779802037 @default.
- W2969486566 hasConcept C31174226 @default.
- W2969486566 hasConcept C501593827 @default.
- W2969486566 hasConcept C61511704 @default.
- W2969486566 hasConcept C71924100 @default.
- W2969486566 hasConcept C86803240 @default.
- W2969486566 hasConcept C89423630 @default.
- W2969486566 hasConcept C90924648 @default.
- W2969486566 hasConcept C94665300 @default.
- W2969486566 hasConceptScore W2969486566C120665830 @default.
- W2969486566 hasConceptScore W2969486566C121332964 @default.
- W2969486566 hasConceptScore W2969486566C126322002 @default.
- W2969486566 hasConceptScore W2969486566C137627325 @default.
- W2969486566 hasConceptScore W2969486566C141071460 @default.
- W2969486566 hasConceptScore W2969486566C167135981 @default.
- W2969486566 hasConceptScore W2969486566C2778602436 @default.
- W2969486566 hasConceptScore W2969486566C2779802037 @default.
- W2969486566 hasConceptScore W2969486566C31174226 @default.
- W2969486566 hasConceptScore W2969486566C501593827 @default.
- W2969486566 hasConceptScore W2969486566C61511704 @default.
- W2969486566 hasConceptScore W2969486566C71924100 @default.
- W2969486566 hasConceptScore W2969486566C86803240 @default.
- W2969486566 hasConceptScore W2969486566C89423630 @default.
- W2969486566 hasConceptScore W2969486566C90924648 @default.
- W2969486566 hasConceptScore W2969486566C94665300 @default.
- W2969486566 hasLocation W29694865661 @default.
- W2969486566 hasOpenAccess W2969486566 @default.
- W2969486566 hasPrimaryLocation W29694865661 @default.
- W2969486566 isParatext "false" @default.
- W2969486566 isRetracted "false" @default.
- W2969486566 magId "2969486566" @default.
- W2969486566 workType "article" @default.