FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969494022> ?p ?o ?g. }

• W2969494022 endingPage "198" @default.
• W2969494022 startingPage "191" @default.
• W2969494022 abstract "Grade groups (GGs) are an important parameter for therapeutic decision making in prostate cancer (Pca) patients. Invasive cribriform and/or intraductal carcinoma (CR/IDC) has an independent prognostic value for disease outcome, but are not included in the GG limiting their clinical use. To perform a proof-of-principle study incorporating CR/IDC in the current GG. All prostate biopsies of 1031 men with screen-detected Pca between 1993 and 2000 were reviewed for the current GG (ranging from 1 to 5) and CR/IDC. The cribriform grade (cGrade) was equal to the GG if CR/IDC was present and GG minus 1 if not. GG1 was cGrade1 if intraductal carcinoma was absent. Biopsy review for GG and CR/IDC. A total of 406 patients had received radical prostatectomy (RP), 508 radiotherapy (RT), 108 surveillance, and eight hormonal therapy, and the treatment was unknown for one patient. Outcome measurements and statistical analysis disease-specific survival (DSS), metastasis-free survival (MFS), and biochemical recurrence–free survival (BCRFS) after 15.1 yr (interquartile range 10.9–19.7 yr) follow-up were compared using Harrell’s C-statistic. The biopsy GGs were 486 GG1, 310 GG2, 104 GG3, 64 GG4, and 67 GG5; cGrade distributions were 738 cGrade1, 102 cGrade2, 91 cGrade3, 58 cGrade4, and 42 cGrade5. The cGrade had a better discriminative value than the GG for DSS (C-index 0.79; 95% confidence interval 0.74–0.83 vs 0.76; 0.71–0.82) and MFS (0.79; 0.74–0.84 vs 0.77; 0.72–0.82). The discriminative value for BCRFS after RP and RT was similar for both models. Different diagnostic, such as use of sextant biopsies, and therapeutic strategies in the 1990s are the limitations of this study. The cGrade is a simple Pca grade modification with better discriminative values for DSS and MFS than the GG, particularly impacting decision making in men with current GG2 Pca. Microscopic grading is an important factor for decision making in prostate cancer (Pca) patients. We show that a simple grade modification better predicts Pca outcome and might improve treatment choices." @default.
• W2969494022 created "2019-08-29" @default.
• W2969494022 creator A5001534857 @default.
• W2969494022 creator A5013424563 @default.
• W2969494022 creator A5024927727 @default.
• W2969494022 creator A5025690030 @default.
• W2969494022 creator A5039867286 @default.
• W2969494022 creator A5046404259 @default.
• W2969494022 creator A5060005820 @default.
• W2969494022 creator A5068826699 @default.
• W2969494022 creator A5079368371 @default.
• W2969494022 creator A5081598999 @default.
• W2969494022 creator A5083000708 @default.
• W2969494022 date "2020-02-01" @default.
• W2969494022 modified "2023-10-16" @default.
• W2969494022 title "Improved Prostate Cancer Biopsy Grading by Incorporation of Invasive Cribriform and Intraductal Carcinoma in the 2014 Grade Groups" @default.
• W2969494022 cites W1711647572 @default.
• W2969494022 cites W1806046400 @default.
• W2969494022 cites W1961674496 @default.
• W2969494022 cites W1990362208 @default.
• W2969494022 cites W2021480933 @default.
• W2969494022 cites W2038264173 @default.
• W2969494022 cites W2042103604 @default.
• W2969494022 cites W2062254183 @default.
• W2969494022 cites W2083043726 @default.
• W2969494022 cites W2092281468 @default.
• W2969494022 cites W2093867637 @default.
• W2969494022 cites W2095761465 @default.
• W2969494022 cites W2133941702 @default.
• W2969494022 cites W2165544861 @default.
• W2969494022 cites W2168391852 @default.
• W2969494022 cites W2319365577 @default.
• W2969494022 cites W2331163623 @default.
• W2969494022 cites W2332713888 @default.
• W2969494022 cites W2340422569 @default.
• W2969494022 cites W2414848281 @default.
• W2969494022 cites W2474446109 @default.
• W2969494022 cites W2491864428 @default.
• W2969494022 cites W2513592679 @default.
• W2969494022 cites W2613476616 @default.
• W2969494022 cites W2747512347 @default.
• W2969494022 cites W2897586354 @default.
• W2969494022 doi "https://doi.org/10.1016/j.eururo.2019.07.051" @default.
• W2969494022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31439369" @default.
• W2969494022 hasPublicationYear "2020" @default.
• W2969494022 type Work @default.
• W2969494022 sameAs 2969494022 @default.
• W2969494022 citedByCount "53" @default.
• W2969494022 countsByYear W29694940222020 @default.
• W2969494022 countsByYear W29694940222021 @default.
• W2969494022 countsByYear W29694940222022 @default.
• W2969494022 countsByYear W29694940222023 @default.
• W2969494022 crossrefType "journal-article" @default.
• W2969494022 hasAuthorship W2969494022A5001534857 @default.
• W2969494022 hasAuthorship W2969494022A5013424563 @default.
• W2969494022 hasAuthorship W2969494022A5024927727 @default.
• W2969494022 hasAuthorship W2969494022A5025690030 @default.
• W2969494022 hasAuthorship W2969494022A5039867286 @default.
• W2969494022 hasAuthorship W2969494022A5046404259 @default.
• W2969494022 hasAuthorship W2969494022A5060005820 @default.
• W2969494022 hasAuthorship W2969494022A5068826699 @default.
• W2969494022 hasAuthorship W2969494022A5079368371 @default.
• W2969494022 hasAuthorship W2969494022A5081598999 @default.
• W2969494022 hasAuthorship W2969494022A5083000708 @default.
• W2969494022 hasBestOaLocation W29694940222 @default.
• W2969494022 hasConcept C119060515 @default.
• W2969494022 hasConcept C121608353 @default.
• W2969494022 hasConcept C126322002 @default.
• W2969494022 hasConcept C126894567 @default.
• W2969494022 hasConcept C127413603 @default.
• W2969494022 hasConcept C143998085 @default.
• W2969494022 hasConcept C147176958 @default.
• W2969494022 hasConcept C2775934546 @default.
• W2969494022 hasConcept C2777154038 @default.
• W2969494022 hasConcept C2777286243 @default.
• W2969494022 hasConcept C2777546739 @default.
• W2969494022 hasConcept C2779466945 @default.
• W2969494022 hasConcept C2780192828 @default.
• W2969494022 hasConcept C2909818935 @default.
• W2969494022 hasConcept C44249647 @default.
• W2969494022 hasConcept C71924100 @default.
• W2969494022 hasConceptScore W2969494022C119060515 @default.
• W2969494022 hasConceptScore W2969494022C121608353 @default.
• W2969494022 hasConceptScore W2969494022C126322002 @default.
• W2969494022 hasConceptScore W2969494022C126894567 @default.
• W2969494022 hasConceptScore W2969494022C127413603 @default.
• W2969494022 hasConceptScore W2969494022C143998085 @default.
• W2969494022 hasConceptScore W2969494022C147176958 @default.
• W2969494022 hasConceptScore W2969494022C2775934546 @default.
• W2969494022 hasConceptScore W2969494022C2777154038 @default.
• W2969494022 hasConceptScore W2969494022C2777286243 @default.
• W2969494022 hasConceptScore W2969494022C2777546739 @default.
• W2969494022 hasConceptScore W2969494022C2779466945 @default.
• W2969494022 hasConceptScore W2969494022C2780192828 @default.
• W2969494022 hasConceptScore W2969494022C2909818935 @default.
• W2969494022 hasConceptScore W2969494022C44249647 @default.
• W2969494022 hasConceptScore W2969494022C71924100 @default.
• W2969494022 hasIssue "2" @default.

• next