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- W2969598413 startingPage "4" @default.
- W2969598413 abstract "Antimicrobial peptides in recent years have gained increased interest among scientists, health professionals and the pharmaceutical companies owing to their therapeutic potential. These are low molecular weight proteins with broad range antimicrobial and immuno modulatory activities against infectious bacteria (Gram positive and Gram negative), viruses and fungi. Inability of micro-organisms to develop resistance against most of the antimicrobial peptide has made them as an efficient product which can greatly impact the new era of antimicrobials. In addition to this these peptides also demonstrates increased efficacy, high specificity, decreased drug interaction, low toxicity, biological diversity and direct attacking properties. Pharmaceutical industries are therefore conducting appropriate clinical trials to develop these peptides as potential therapeutic drugs. More than 60 peptide drugs have already reached the market and several hundreds of novel therapeutic peptides are in preclinical and clinical development. Rational designing can be used further to modify the chemical and physical properties of existing peptides. This mini review will discuss the sources, mechanism and recent therapeutic applications of antimicrobial peptides in treatment of infectious diseases." @default.
- W2969598413 created "2019-08-29" @default.
- W2969598413 creator A5026205185 @default.
- W2969598413 creator A5090896522 @default.
- W2969598413 date "2019-12-10" @default.
- W2969598413 modified "2023-10-06" @default.
- W2969598413 title "Mini Review on Antimicrobial Peptides, Sources, Mechanism and Recent Applications" @default.
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