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• W2969645849 endingPage "485" @default.
• W2969645849 startingPage "441" @default.
• W2969645849 abstract "The Golgi apparatus is a central intracellular membrane-bound organelle with key functions in trafficking, processing, and sorting of newly synthesized membrane and secretory proteins and lipids. To best perform these functions, Golgi membranes form a unique stacked structure. The Golgi structure is dynamic but tightly regulated; it undergoes rapid disassembly and reassembly during the cell cycle of mammalian cells and is disrupted under certain stress and pathological conditions. In the past decade, significant amount of effort has been made to reveal the molecular mechanisms that regulate the Golgi membrane architecture and function. Here we review the major discoveries in the mechanisms of Golgi structure formation, regulation, and alteration in relation to its functions in physiological and pathological conditions to further our understanding of Golgi structure and function in health and diseases." @default.
• W2969645849 created "2019-08-29" @default.
• W2969645849 creator A5006266328 @default.
• W2969645849 creator A5010957213 @default.
• W2969645849 creator A5061481399 @default.
• W2969645849 date "2019-01-01" @default.
• W2969645849 modified "2023-10-10" @default.
• W2969645849 title "Golgi Structure and Function in Health, Stress, and Diseases" @default.
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