FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969653586> ?p ?o ?g. }

• W2969653586 endingPage "275" @default.
• W2969653586 startingPage "271" @default.
• W2969653586 abstract "<h3>Objectives</h3> To improve the disinfection methods for materials with a non-sterile surface to be used in aseptic handling. <h3>Methods</h3> The surface bioburden on ampoules (A) and injection vials (IV) is determined by contact plates and total immersion. The occurrence of spore-forming bacteria is determined by strain colouring and matrix-assisted laser desorption ionisation-time of flight mass spectrometry. The disinfection procedures of non-sterile materials in 10 hospital pharmacies are judged by observing. <h3>Results</h3> After wiping according to local disinfection methods, the mean surface bioburden determined by contact plates in 10 hospital pharmacies is 0.36 (plastic A), 0.50 (glass A) and 0.29 colony-forming unit (cfu) (IV). The observers found great differences in accuracy of wiping and degree of wetting the sterile gauzes. After improved wiping with commercially available alcohol impregnated sterile wipes and a two-towel technique (one-step TT disinfection), the mean surface bioburden determined by contact plates is 0.03 (plastic A), 0.2 (glass A) and 0.13 cfu (IV). Further improvement can be reached by submerging A and IV in ethanol 70% followed by improved wiping (two-step TT disinfection), but still micro-organisms will remain (mean surface bioburden determined by total immersion is 0 (plastic A) and 0.3 cfu (IV); glass A not determined). Two-step TT disinfection is more labour intensive. Spilling of alcohol is another disadvantage. However, we presume one-step TT disinfection is effective enough in daily practice. Routine surface bioburden determinations have to prove this. The effectiveness of the combination of spray and wipe is not examined because we observed a quick disappearance of alcohols from vertical as well as horizontal surfaces, which shortens the contact time to far below the advised 2 min. Spore-forming bacteria disappear as quickly as other micro-organisms during disinfection by alcohols. <h3>Conclusion</h3> Local disinfection procedures can be improved. Complete removal of micro-organisms from materials with a non-sterile surface, even after two-step TT disinfection, is impossible. Routine surface bioburden determinations have to prove if one-step TT disinfection is effective enough." @default.
• W2969653586 created "2019-08-29" @default.
• W2969653586 creator A5018163150 @default.
• W2969653586 creator A5024992185 @default.
• W2969653586 creator A5027923445 @default.
• W2969653586 creator A5060465721 @default.
• W2969653586 creator A5081610474 @default.
• W2969653586 date "2019-08-24" @default.
• W2969653586 modified "2023-10-02" @default.
• W2969653586 title "Improving the aseptic transfer procedures in hospital pharmacies. Part B: evaluation of disinfection methods for materials with a non-sterile surface" @default.
• W2969653586 cites W1825921272 @default.
• W2969653586 cites W1862885461 @default.
• W2969653586 cites W1997028248 @default.
• W2969653586 cites W2163971377 @default.
• W2969653586 cites W2268257652 @default.
• W2969653586 cites W2328066049 @default.
• W2969653586 cites W2950252151 @default.
• W2969653586 cites W4256037471 @default.
• W2969653586 doi "https://doi.org/10.1136/ejhpharm-2018-001673" @default.
• W2969653586 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8403772" @default.
• W2969653586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34426480" @default.
• W2969653586 hasPublicationYear "2019" @default.
• W2969653586 type Work @default.
• W2969653586 sameAs 2969653586 @default.
• W2969653586 citedByCount "9" @default.
• W2969653586 countsByYear W29696535862019 @default.
• W2969653586 countsByYear W29696535862020 @default.
• W2969653586 countsByYear W29696535862021 @default.
• W2969653586 countsByYear W29696535862022 @default.
• W2969653586 countsByYear W29696535862023 @default.
• W2969653586 crossrefType "journal-article" @default.
• W2969653586 hasAuthorship W2969653586A5018163150 @default.
• W2969653586 hasAuthorship W2969653586A5024992185 @default.
• W2969653586 hasAuthorship W2969653586A5027923445 @default.
• W2969653586 hasAuthorship W2969653586A5060465721 @default.
• W2969653586 hasAuthorship W2969653586A5081610474 @default.
• W2969653586 hasBestOaLocation W29696535861 @default.
• W2969653586 hasConcept C141071460 @default.
• W2969653586 hasConcept C159985019 @default.
• W2969653586 hasConcept C181268634 @default.
• W2969653586 hasConcept C192562407 @default.
• W2969653586 hasConcept C196762363 @default.
• W2969653586 hasConcept C28845197 @default.
• W2969653586 hasConcept C34008175 @default.
• W2969653586 hasConcept C71924100 @default.
• W2969653586 hasConceptScore W2969653586C141071460 @default.
• W2969653586 hasConceptScore W2969653586C159985019 @default.
• W2969653586 hasConceptScore W2969653586C181268634 @default.
• W2969653586 hasConceptScore W2969653586C192562407 @default.
• W2969653586 hasConceptScore W2969653586C196762363 @default.
• W2969653586 hasConceptScore W2969653586C28845197 @default.
• W2969653586 hasConceptScore W2969653586C34008175 @default.
• W2969653586 hasConceptScore W2969653586C71924100 @default.
• W2969653586 hasIssue "5" @default.
• W2969653586 hasLocation W29696535861 @default.
• W2969653586 hasLocation W29696535862 @default.
• W2969653586 hasLocation W29696535863 @default.
• W2969653586 hasLocation W29696535864 @default.
• W2969653586 hasLocation W29696535865 @default.
• W2969653586 hasLocation W29696535866 @default.
• W2969653586 hasLocation W29696535867 @default.
• W2969653586 hasOpenAccess W2969653586 @default.
• W2969653586 hasPrimaryLocation W29696535861 @default.
• W2969653586 hasRelatedWork W1997028248 @default.
• W2969653586 hasRelatedWork W2059928903 @default.
• W2969653586 hasRelatedWork W2350665673 @default.
• W2969653586 hasRelatedWork W2391971773 @default.
• W2969653586 hasRelatedWork W2902587028 @default.
• W2969653586 hasRelatedWork W2950252151 @default.
• W2969653586 hasRelatedWork W2969653586 @default.
• W2969653586 hasRelatedWork W2982672309 @default.
• W2969653586 hasRelatedWork W4229714907 @default.
• W2969653586 hasRelatedWork W4380762828 @default.
• W2969653586 hasVolume "28" @default.
• W2969653586 isParatext "false" @default.
• W2969653586 isRetracted "false" @default.
• W2969653586 magId "2969653586" @default.
• W2969653586 workType "article" @default.