Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969783511> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2969783511 abstract "Sub-Saharan Africa accounts for 25% of the estimated global 325 million people with chronic hepatitis B and C virus infections. Weak blood transfusion systems facilitate the spread of both hepatitis B and C virus infections. This is worsened by the absence of sustainable quality assurance programs and perennial shortage of sensitive screening kits. We aim to compare the validity of rapid diagnostic tests (RDTs) with the World Health Organization-recommended quality-assured enzyme-linked immunosorbent assay (ELISA) screening method for these viruses.We conducted a cross-sectional study on consecutive blood donor samples. Two hundred and sixty-four blood donor samples screened for hepatitis B and C viruses using RDTs were retested at a National blood transfusion service, Kaduna, Nigeria. Data were analyzed using OpenEpi version 3.01 to determine the sensitivity, specificity, and predictive values of RDTs versus ELISA.The sensitivities of the RDTs at 95% confidence interval (CI) were low - 40% (19.8-64.3) and 50.0% (18.8-81.2) - for hepatitis B surface antigen (HBsAg) and hepatitis C virus (HCV) antibody, respectively. The specificities and 95% CI were high - 99.9% (97.8-99.9) and 100.0% (98.5-100) for HBsAg and HCV antibody, respectively.Predonation RDTs screening of blood donor samples for hepatitis B virus and HCV in hospital donation units performed poorly compared to quality-assured ELISA screening in Kaduna. The risk of transmitting viral hepatitis through blood transfusion still exists. We recommend quality-assured ELISA screening of all donated units for HBsAg and HCV antibody to reduce the risk of these transfusion-transmitted infections." @default.
- W2969783511 created "2019-08-29" @default.
- W2969783511 creator A5035619408 @default.
- W2969783511 creator A5042747733 @default.
- W2969783511 creator A5063010244 @default.
- W2969783511 creator A5070470617 @default.
- W2969783511 creator A5071030939 @default.
- W2969783511 creator A5071534362 @default.
- W2969783511 creator A5075113811 @default.
- W2969783511 creator A5089899431 @default.
- W2969783511 date "2019-01-01" @default.
- W2969783511 modified "2023-09-23" @default.
- W2969783511 title "Towards 2030 target for hepatitis B and C viruses elimination: Assessing the validity of predonation rapid diagnostic tests versus enzyme-linked immunosorbent assay in state hospitals in Kaduna, Nigeria" @default.
- W2969783511 cites W1986215900 @default.
- W2969783511 cites W2009738592 @default.
- W2969783511 cites W2031557385 @default.
- W2969783511 cites W2040108618 @default.
- W2969783511 cites W2055704827 @default.
- W2969783511 cites W2062518259 @default.
- W2969783511 cites W2064212236 @default.
- W2969783511 cites W2130414834 @default.
- W2969783511 cites W2144150348 @default.
- W2969783511 cites W2169068584 @default.
- W2969783511 cites W2405526501 @default.
- W2969783511 cites W2418274416 @default.
- W2969783511 cites W2532839950 @default.
- W2969783511 cites W286425085 @default.
- W2969783511 cites W4210612358 @default.
- W2969783511 doi "https://doi.org/10.4103/nmj.nmj_93_18" @default.
- W2969783511 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6737797" @default.
- W2969783511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31543570" @default.
- W2969783511 hasPublicationYear "2019" @default.
- W2969783511 type Work @default.
- W2969783511 sameAs 2969783511 @default.
- W2969783511 citedByCount "1" @default.
- W2969783511 countsByYear W29697835112021 @default.
- W2969783511 crossrefType "journal-article" @default.
- W2969783511 hasAuthorship W2969783511A5035619408 @default.
- W2969783511 hasAuthorship W2969783511A5042747733 @default.
- W2969783511 hasAuthorship W2969783511A5063010244 @default.
- W2969783511 hasAuthorship W2969783511A5070470617 @default.
- W2969783511 hasAuthorship W2969783511A5071030939 @default.
- W2969783511 hasAuthorship W2969783511A5071534362 @default.
- W2969783511 hasAuthorship W2969783511A5075113811 @default.
- W2969783511 hasAuthorship W2969783511A5089899431 @default.
- W2969783511 hasBestOaLocation W29697835112 @default.
- W2969783511 hasConcept C126322002 @default.
- W2969783511 hasConcept C138885662 @default.
- W2969783511 hasConcept C159047783 @default.
- W2969783511 hasConcept C159654299 @default.
- W2969783511 hasConcept C194051981 @default.
- W2969783511 hasConcept C203014093 @default.
- W2969783511 hasConcept C2522874641 @default.
- W2969783511 hasConcept C2776408679 @default.
- W2969783511 hasConcept C2776455275 @default.
- W2969783511 hasConcept C2777382497 @default.
- W2969783511 hasConcept C2777410769 @default.
- W2969783511 hasConcept C2778137410 @default.
- W2969783511 hasConcept C2780014101 @default.
- W2969783511 hasConcept C2780593183 @default.
- W2969783511 hasConcept C41895202 @default.
- W2969783511 hasConcept C71924100 @default.
- W2969783511 hasConceptScore W2969783511C126322002 @default.
- W2969783511 hasConceptScore W2969783511C138885662 @default.
- W2969783511 hasConceptScore W2969783511C159047783 @default.
- W2969783511 hasConceptScore W2969783511C159654299 @default.
- W2969783511 hasConceptScore W2969783511C194051981 @default.
- W2969783511 hasConceptScore W2969783511C203014093 @default.
- W2969783511 hasConceptScore W2969783511C2522874641 @default.
- W2969783511 hasConceptScore W2969783511C2776408679 @default.
- W2969783511 hasConceptScore W2969783511C2776455275 @default.
- W2969783511 hasConceptScore W2969783511C2777382497 @default.
- W2969783511 hasConceptScore W2969783511C2777410769 @default.
- W2969783511 hasConceptScore W2969783511C2778137410 @default.
- W2969783511 hasConceptScore W2969783511C2780014101 @default.
- W2969783511 hasConceptScore W2969783511C2780593183 @default.
- W2969783511 hasConceptScore W2969783511C41895202 @default.
- W2969783511 hasConceptScore W2969783511C71924100 @default.
- W2969783511 hasLocation W29697835111 @default.
- W2969783511 hasLocation W29697835112 @default.
- W2969783511 hasLocation W29697835113 @default.
- W2969783511 hasLocation W29697835114 @default.
- W2969783511 hasOpenAccess W2969783511 @default.
- W2969783511 hasPrimaryLocation W29697835111 @default.
- W2969783511 hasRelatedWork W172797762 @default.
- W2969783511 hasRelatedWork W1848188855 @default.
- W2969783511 hasRelatedWork W1928803268 @default.
- W2969783511 hasRelatedWork W1966571063 @default.
- W2969783511 hasRelatedWork W1982841137 @default.
- W2969783511 hasRelatedWork W2069203385 @default.
- W2969783511 hasRelatedWork W3016505316 @default.
- W2969783511 hasRelatedWork W3190218220 @default.
- W2969783511 hasRelatedWork W4288802448 @default.
- W2969783511 hasRelatedWork W2377450416 @default.
- W2969783511 isParatext "false" @default.
- W2969783511 isRetracted "false" @default.
- W2969783511 magId "2969783511" @default.
- W2969783511 workType "article" @default.