FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2969856581> ?p ?o ?g. }

• W2969856581 endingPage "239821281988308" @default.
• W2969856581 startingPage "239821281988308" @default.
• W2969856581 abstract "Maternal immune activation is consistently associated with elevated risk for multiple psychiatric disorders in the affected offspring. Related to this, an important goal of our work is to explore the impact of maternal immune activation effects across the lifespan. In this context, we recently reported the effects of polyriboinosinic-polyribocytidylic acid–induced maternal immune activation at gestational day 15, immediately prior to birth, at gestational day 21 and again at post-natal day 21, providing a systematic assessment of plasma interleukin 6, body temperature and weight alterations in pregnant rats and preliminary evidence for gross morphological changes and microglial neuropathology in both male and female offsprings at these time points. Here, we sought to complement and extend these data by characterising in more detail the mesoscale impact of gestational polyriboinosinic-polyribocytidylic acid exposure at gestational day 15 on the neuroanatomy of the juvenile (post-natal day 21) rat brain using high-resolution, ex vivo anatomical magnetic resonance imaging in combination with atlas-based segmentation. Our preliminary data suggest subtle neuroanatomical effects of gestational polyriboinosinic-polyribocytidylic acid exposure (n = 10) relative to saline controls (n = 10) at this time-point. Specifically, we found an increase in the relative volume of the diagonal domain in polyriboinosinic-polyribocytidylic acid offspring (p < 0.01 uncorrected), which just failed to pass stringent multiple comparisons correction (actual q = 0.07). No statistically significant microstructural alterations were detectable using diffusion tensor imaging. Further studies are required to map the proximal effects of maternal immune activation on the developing rodent brain from foetal to early post-natal life and confirm our findings herein." @default.
• W2969856581 created "2019-08-29" @default.
• W2969856581 creator A5003403911 @default.
• W2969856581 creator A5058165911 @default.
• W2969856581 creator A5069186555 @default.
• W2969856581 creator A5081183910 @default.
• W2969856581 creator A5081512499 @default.
• W2969856581 creator A5087369165 @default.
• W2969856581 date "2019-01-01" @default.
• W2969856581 modified "2023-10-18" @default.
• W2969856581 title "Mapping the impact of exposure to maternal immune activation on juvenile Wistar rat brain macro- and microstructure during early post-natal development" @default.
• W2969856581 cites W1876555651 @default.
• W2969856581 cites W1945545951 @default.
• W2969856581 cites W1946401928 @default.
• W2969856581 cites W1963603721 @default.
• W2969856581 cites W1965432000 @default.
• W2969856581 cites W1970565358 @default.
• W2969856581 cites W1974251035 @default.
• W2969856581 cites W1981833273 @default.
• W2969856581 cites W1984453610 @default.
• W2969856581 cites W1985811700 @default.
• W2969856581 cites W1994600097 @default.
• W2969856581 cites W1994874327 @default.
• W2969856581 cites W1999072976 @default.
• W2969856581 cites W2002689596 @default.
• W2969856581 cites W2005223778 @default.
• W2969856581 cites W2006792282 @default.
• W2969856581 cites W2020651859 @default.
• W2969856581 cites W2021909736 @default.
• W2969856581 cites W2025367651 @default.
• W2969856581 cites W2040408325 @default.
• W2969856581 cites W2042662378 @default.
• W2969856581 cites W2055615422 @default.
• W2969856581 cites W2084550269 @default.
• W2969856581 cites W2105077280 @default.
• W2969856581 cites W2111005891 @default.
• W2969856581 cites W2117140276 @default.
• W2969856581 cites W2117340355 @default.
• W2969856581 cites W2123403544 @default.
• W2969856581 cites W2125181231 @default.
• W2969856581 cites W2127309075 @default.
• W2969856581 cites W2132671831 @default.
• W2969856581 cites W2136145485 @default.
• W2969856581 cites W2162689369 @default.
• W2969856581 cites W2163274894 @default.
• W2969856581 cites W2301077564 @default.
• W2969856581 cites W2509368961 @default.
• W2969856581 cites W2515897135 @default.
• W2969856581 cites W2560077862 @default.
• W2969856581 cites W2599826853 @default.
• W2969856581 cites W2694505964 @default.
• W2969856581 cites W2724285371 @default.
• W2969856581 cites W2745332281 @default.
• W2969856581 cites W2770588420 @default.
• W2969856581 cites W2797215799 @default.
• W2969856581 cites W2806744988 @default.
• W2969856581 cites W2811117516 @default.
• W2969856581 cites W2883831786 @default.
• W2969856581 cites W2888504723 @default.
• W2969856581 cites W2890708734 @default.
• W2969856581 cites W2892154404 @default.
• W2969856581 cites W2899359465 @default.
• W2969856581 cites W2912308370 @default.
• W2969856581 cites W2914916753 @default.
• W2969856581 cites W2924293916 @default.
• W2969856581 cites W2954365414 @default.
• W2969856581 cites W2977883299 @default.
• W2969856581 cites W2915570911 @default.
• W2969856581 doi "https://doi.org/10.1177/2398212819883086" @default.
• W2969856581 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6861131" @default.
• W2969856581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31742236" @default.
• W2969856581 hasPublicationYear "2019" @default.
• W2969856581 type Work @default.
• W2969856581 sameAs 2969856581 @default.
• W2969856581 citedByCount "3" @default.
• W2969856581 countsByYear W29698565812021 @default.
• W2969856581 countsByYear W29698565812022 @default.
• W2969856581 countsByYear W29698565812023 @default.
• W2969856581 crossrefType "journal-article" @default.
• W2969856581 hasAuthorship W2969856581A5003403911 @default.
• W2969856581 hasAuthorship W2969856581A5058165911 @default.
• W2969856581 hasAuthorship W2969856581A5069186555 @default.
• W2969856581 hasAuthorship W2969856581A5081183910 @default.
• W2969856581 hasAuthorship W2969856581A5081512499 @default.
• W2969856581 hasAuthorship W2969856581A5087369165 @default.
• W2969856581 hasBestOaLocation W29698565811 @default.
• W2969856581 hasConcept C112672928 @default.
• W2969856581 hasConcept C115961737 @default.
• W2969856581 hasConcept C126322002 @default.
• W2969856581 hasConcept C134018914 @default.
• W2969856581 hasConcept C151730666 @default.
• W2969856581 hasConcept C167654180 @default.
• W2969856581 hasConcept C169760540 @default.
• W2969856581 hasConcept C203014093 @default.
• W2969856581 hasConcept C2779234561 @default.
• W2969856581 hasConcept C2779343474 @default.
• W2969856581 hasConcept C42407357 @default.
• W2969856581 hasConcept C46973012 @default.

• next