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- W2969857584 abstract "The studies which are investigating the relationship between HLA-B27 and the clinical findings in psoriatic arthritis (PsA) are too limited in the literature and also in our country. In this study, we aimed to find out the frequency of HLA-B27 and compare the demographic, clinical and radiological findings in patients with PsA. Fifty one patients who have been diagnosed with PsA enrolled in the study. The demographic characteristics, the clinical and radiological findings, the treatment modalities, and the HLA-B27 gene analysis results of the patients were recorded by scanning the follow-up charts of all patients. HLA-B27 analysis of patients were performed by using real-time PCR in Kocaeli University, in Faculty of Medicine, in Department of Medical Genetics. HLA-B27 was positive in 8 of 51 patients (15.69%). In patients with axial involvement and peripheral involvement, the rate of HLA-B27 pozitivity was 37.5%, 11.6%, respectively (p=0.099). There was no relationship between the presence of HLA-B27 and with other clinical findings. In our study, HLA-B27 positivity rate was similar to the values found in recent publications. The results of HLA-B27 supports the increased risk of axial involvement in PsA patients." @default.
- W2969857584 created "2019-08-29" @default.
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- W2969857584 date "2014-03-01" @default.
- W2969857584 modified "2023-10-15" @default.
- W2969857584 title "Psoriatik Artritli Hastalarda HLA-B27 Sıklığı ve Demografik, Klinik, Radyolojik Bulgularla İlişkisi" @default.
- W2969857584 hasPublicationYear "2014" @default.
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