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- W2969898068 abstract "Abstract The wo protein and its downstream gene, SlCycB2 have been demonstrated to regulate the trichome development in tomato. It was shown that only gain-of-function mutant form of wo, Wo v (wo woolly motif mutant allele) could induce the increase of trichome density. However, it is still unclear the relationships between wo, Wo v and SlCycB2 in trichome regulation. In this study, we demonstrated Nbwo (NbWo v ) directly regulated the expressions NbCycB2 by binding to the promoter of NbCycB2 and its genomic sequences. As a feedback regulation, NbCycB2 negatively regulates the trichome formation by repressing Nbwo activity at protein level. We further found that the mutations of Nbwo woolly motif could prevent repression of NbWo v by NbCycB2, which results in the significant increase of active Nbwo proteins, trichome density and branches. Our results revealed a novel reciprocal mechanism between NbCycB2 and Nbwo during the trichome formation in Nicotiana benthamiana . Highlight NbCycB2 is specifically expressed in trichomes of Nicotiana benthamiana and represses the Nbwo activity via a negative feedback loop in tobacco trichome developmemt." @default.
- W2969898068 created "2019-08-29" @default.
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- W2969898068 date "2019-08-20" @default.
- W2969898068 modified "2023-09-30" @default.
- W2969898068 title "NbCycB2 represses Nbwo activity via a negative feedback loop in the tobacco trichome developmemt" @default.
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- W2969898068 doi "https://doi.org/10.1101/740126" @default.
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