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- W2970009826 abstract "Photodynamic therapy (PDT) is a method of the treatment of localized cancers, based ona photochemical reaction between a light-activated molecule or photosensitizer (PS), light,and molecular oxygen. Correct choice of PS is of fundamental importance for PDT effcacy.Despite numerous studies in this feld, most known PS have some drawbacks, e.g. lack ofspecifcity and aggregation in aqueous media. Consequently, the search for an ideal PS is essential for further development of PDT. Here we review classifcation and analyse main featuresof different generations of PS and describe the mechanisms of their action. Various methodsof targeted delivery of PS to tumor cells are discussed. The advantages of PS nanoparticleswith the effect of aggregation-induced emission (AIE) over the classic photosensitizers arepresented. A possibility of practical application of such light-emitting structures in cancerphototherapy is shown." @default.
- W2970009826 created "2019-09-05" @default.
- W2970009826 creator A5001519258 @default.
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- W2970009826 date "2019-08-28" @default.
- W2970009826 modified "2023-10-01" @default.
- W2970009826 title "Nanoparticles-based photosensitizers with effect of aggregation-induced emission" @default.
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- W2970009826 doi "https://doi.org/10.7124/bc.000a08" @default.
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