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• W2970126667 abstract "Background: A characteristic of acute lung injury (ALI) is the inflammatory damage of alveolar fluid transport. Lipoxins are endogenous lipids involving in the resolution of inflammation. It is found that lipoxin A4 (LXA4) has the distinct properties to improve the anti-edema and pro-resolution function in inflammation. Since aquaporins (AQPs) have essential roles in the integrity of barrier function during fluid transport, especially AQP5 in the maintaining of the epithelium permeability, the current study is aimed to evaluate the potential role of LXA4 in regulating alveolar fluid clearance (AFC) during fluid transport and the corresponding change of AQP5 in the lung." @default.
• W2970126667 created "2019-09-05" @default.
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• W2970126667 date "2019-08-01" @default.
• W2970126667 modified "2023-09-27" @default.
• W2970126667 title "Lipoxin A4 ameliorates alveolar fluid clearance disturbance in lipopolysaccharide-induced lung injury via aquaporin 5 and MAPK signaling pathway" @default.
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• W2970126667 doi "https://doi.org/10.21037/jtd.2019.08.86" @default.
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