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- W297017098 abstract "The mechanisms through which estrogens induce breast carcinogenesis have not been definitely unraveled, although corresponding catechol and quinine metabolite formation is known to produce ROS. There are two main hypotheses about how estrogen initiates cancer: one through estrogen receptor- mediated processes and the other by DNA damage caused from the interaction of specific estrogen metabolites with DNA (see Figure 1 for the major pathway of estrogen activation in the for-mation of depurinating estrogen-DNA adducts)." @default.
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- W297017098 date "2009-09-20" @default.
- W297017098 modified "2023-09-27" @default.
- W297017098 title "DNA Adduct Formation of 17β-Estradiol in MCF-7 Human Breast Cancer Cells" @default.
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- W297017098 doi "https://doi.org/10.5012/bkcs.2009.30.9.2125" @default.
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