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- W2970536711 abstract "The modern genomic era has seen remarkable advancement in our understanding of the molecular basis for disease, yet translation of basic discoveries into new disease treatments has arguably lagged behind. Recently, breakthroughs in genome editing technologies have created hope for their potential to directly treat the genetic causes of disease. Like any therapeutic intervention, genome editing should be considered in light of its potential risks and benefits. In this review, we highlight the promise of genome editing therapies, as well as the conceptual and technical barriers to their clinical application, with a special emphasis on hematologic malignancies." @default.
- W2970536711 created "2019-09-05" @default.
- W2970536711 creator A5020724887 @default.
- W2970536711 creator A5071223660 @default.
- W2970536711 date "2020-01-27" @default.
- W2970536711 modified "2023-10-17" @default.
- W2970536711 title "Genome Editing and Hematologic Malignancy" @default.
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- W2970536711 doi "https://doi.org/10.1146/annurev-med-052318-100741" @default.
- W2970536711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31469969" @default.
- W2970536711 hasPublicationYear "2020" @default.
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