FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2970569968> ?p ?o ?g. }

• W2970569968 endingPage "545" @default.
• W2970569968 startingPage "537" @default.
• W2970569968 abstract "BACKGROUND Lentigo maligna (LM) is associated with disproportionately high surgical morbidity. OBJECTIVE The authors report on 2 strategies to reduce the surgical morbidity associated with LM. METHODS Forty LM lesions were removed with excisional biopsies without margins and closed with purse-string sutures. Invasive cases underwent staged excisions with 10-mm margins. Cases without invasion were treated with neoadjuvant topical imiquimod 5% cream (5 d/wk × 8 weeks) followed by conservative staged excisions with 2-mm margins using radial sections stained with hematoxylin and eosin and immunostaining with Mart-1, with or without SOX10. RESULTS Invasion was detected in 12/40 (30%) of the excisional biopsy specimens (average depth 0.45 mm). No invasion was detected in 28/40 (70%). All 24 patients who completed neoadjuvant topical imiquimod 5% cream before staged excisions had negative first-stage margins at 2 mm. Compared with average published margins for LM, this represents a 71.4% reduction in the required margin and an average reduction in the final surgical defect by 74%. CONCLUSION LM treatment by excisional biopsies with a purse-string closure enables accurate tumor staging and contracts the tumor footprint to its minimal size. Subsequent neoadjuvant imiquimod followed by a conservative staged excision with 2-mm margins allows for removal of LM with decreased surgical morbidity." @default.
• W2970569968 created "2019-09-05" @default.
• W2970569968 creator A5061665938 @default.
• W2970569968 creator A5089644092 @default.
• W2970569968 date "2020-04-01" @default.
• W2970569968 modified "2023-10-18" @default.
• W2970569968 title "Strategies for Reducing Final Surgical Defect Sizes in the Treatment of Lentigo Maligna" @default.
• W2970569968 cites W1725569650 @default.
• W2970569968 cites W1964281586 @default.
• W2970569968 cites W1965652319 @default.
• W2970569968 cites W1967786291 @default.
• W2970569968 cites W1972868622 @default.
• W2970569968 cites W1973893735 @default.
• W2970569968 cites W1980974844 @default.
• W2970569968 cites W1981191236 @default.
• W2970569968 cites W1986769762 @default.
• W2970569968 cites W1989099193 @default.
• W2970569968 cites W1990585347 @default.
• W2970569968 cites W1995475210 @default.
• W2970569968 cites W1996102225 @default.
• W2970569968 cites W2000559124 @default.
• W2970569968 cites W2013423311 @default.
• W2970569968 cites W2013586830 @default.
• W2970569968 cites W2014982216 @default.
• W2970569968 cites W2018453350 @default.
• W2970569968 cites W2021791865 @default.
• W2970569968 cites W2023461468 @default.
• W2970569968 cites W2025430321 @default.
• W2970569968 cites W2028710709 @default.
• W2970569968 cites W2031044818 @default.
• W2970569968 cites W2034657988 @default.
• W2970569968 cites W2037178997 @default.
• W2970569968 cites W2038079714 @default.
• W2970569968 cites W2043358335 @default.
• W2970569968 cites W2058649747 @default.
• W2970569968 cites W2059314960 @default.
• W2970569968 cites W2059352268 @default.
• W2970569968 cites W2065135904 @default.
• W2970569968 cites W2073961418 @default.
• W2970569968 cites W2077186226 @default.
• W2970569968 cites W2084119984 @default.
• W2970569968 cites W2085340320 @default.
• W2970569968 cites W2094428444 @default.
• W2970569968 cites W2096788382 @default.
• W2970569968 cites W2097094086 @default.
• W2970569968 cites W2101464127 @default.
• W2970569968 cites W2111030530 @default.
• W2970569968 cites W2111311285 @default.
• W2970569968 cites W2118863192 @default.
• W2970569968 cites W2122120209 @default.
• W2970569968 cites W2133400382 @default.
• W2970569968 cites W2149561661 @default.
• W2970569968 cites W2151799602 @default.
• W2970569968 cites W2153163246 @default.
• W2970569968 cites W2158537617 @default.
• W2970569968 cites W2160075129 @default.
• W2970569968 cites W2161255752 @default.
• W2970569968 cites W2163915096 @default.
• W2970569968 cites W2167081628 @default.
• W2970569968 cites W2319313638 @default.
• W2970569968 cites W2321991564 @default.
• W2970569968 cites W2323353059 @default.
• W2970569968 cites W2329842425 @default.
• W2970569968 cites W2392343002 @default.
• W2970569968 cites W2418829314 @default.
• W2970569968 cites W2463538100 @default.
• W2970569968 cites W2563312092 @default.
• W2970569968 cites W2586496456 @default.
• W2970569968 cites W4242552027 @default.
• W2970569968 cites W4248295676 @default.
• W2970569968 doi "https://doi.org/10.1097/dss.0000000000002099" @default.
• W2970569968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31464705" @default.
• W2970569968 hasPublicationYear "2020" @default.
• W2970569968 type Work @default.
• W2970569968 sameAs 2970569968 @default.
• W2970569968 citedByCount "6" @default.
• W2970569968 countsByYear W29705699682021 @default.
• W2970569968 countsByYear W29705699682022 @default.
• W2970569968 countsByYear W29705699682023 @default.
• W2970569968 crossrefType "journal-article" @default.
• W2970569968 hasAuthorship W2970569968A5061665938 @default.
• W2970569968 hasAuthorship W2970569968A5089644092 @default.
• W2970569968 hasConcept C126838900 @default.
• W2970569968 hasConcept C141071460 @default.
• W2970569968 hasConcept C159110652 @default.
• W2970569968 hasConcept C16005928 @default.
• W2970569968 hasConcept C2775934546 @default.
• W2970569968 hasConcept C2777393561 @default.
• W2970569968 hasConcept C2777658100 @default.
• W2970569968 hasConcept C2778913397 @default.
• W2970569968 hasConcept C2779112978 @default.
• W2970569968 hasConcept C502942594 @default.
• W2970569968 hasConcept C71924100 @default.
• W2970569968 hasConceptScore W2970569968C126838900 @default.
• W2970569968 hasConceptScore W2970569968C141071460 @default.
• W2970569968 hasConceptScore W2970569968C159110652 @default.
• W2970569968 hasConceptScore W2970569968C16005928 @default.
• W2970569968 hasConceptScore W2970569968C2775934546 @default.

• next