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- W2970751775 abstract "Purpose We have developed a diagnostic technique to evaluate hepatic steatosis using the attenuation coefficient (ATT) on ultrasound B mode. A controlled attenuation parameter (CAP) by vibration-controlled transient elastography (VCTE) has also been used to evaluate hepatic steatosis. As that method uses ultrasound A mode, visualizing the liver in real time is difficult. We planned this clinical study to evaluate the diagnostic advantage of our technique using ATT compared with CAP. Materials and Methods All participants provided written informed consent, and study protocols were approved by the institutional ethics committee. Liver biopsy had been performed for 94 patients with non-alcoholic fatty liver disease, and at the same time we evaluated ATT and CAP. An M-probe was used for CAP measurement. Data from ATT and CAP were compared with steatosis grade from liver specimens. Results ATT was measured in all cases. Areas under the receiver operating characteristic curve (AUC-ROCs) for ≥ S1 were 0.74 and 0.81 for ATT and CAP, respectively. AUC-ROCs for ≥ S2 were 0.80 and 0.85, and for S3 were 0.96 and 0.98, respectively. ATT measurement can evaluate hepatic steatosis compared with histology, offering similar diagnostic strength to CAP measurement. No significant differences between ATT and CAP were observed, but evaluation on ultrasound B mode is convenient and quick, especially for patients with subcutaneous fat thickness ≥ 2 cm. Conclusion New diagnostic techniques using ATT allow similar evaluation of hepatic steatosis to CAP, and evaluation is quicker and more convenient in ultrasound B mode than in ultrasound A mode." @default.
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- W2970751775 date "2019-01-01" @default.
- W2970751775 modified "2023-09-27" @default.
- W2970751775 title "New diagnostic method for hepatic steatosis using attenuation measurement by ultrasound B mode" @default.
- W2970751775 doi "https://doi.org/10.1016/j.ultrasmedbio.2019.07.338" @default.
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