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- W2970805220 abstract "Abstract Pelargonium graveolens is a wild predecessor to rose-scented geranium hybrids prized for their essential oils used as fragrances and flavorings. However, little is known about their biosynthesis. Here we present metabolic evidence that at least two distinct monoterpene biosynthetic pathways contribute to their volatile profiles, namely, cyclic p-menthanes such as (−)-isomenthone and acyclic monoterpene alcohols such as geraniol and (−)-citronellol and their derivatives (referred to here as citronelloid monoterpenes). We established their common origin via the 2C-methyl-d-erythritol-4-phosphate pathway but found no indication these pathways share common intermediates beyond geranyl diphosphate. Untargeted volatile profiling of 22 seed-grown P. graveolens lines demonstrated distinct chemotypes that preferentially accumulate (−)-isomenthone, geraniol, or (−)-citronellol along with approximately 85 minor volatile products. Whole plant 13CO2 isotopic labeling performed under physiological conditions permitted us to measure the in vivo rates of monoterpenoid accumulation in these lines and quantify differences in metabolic modes between chemotypes. We further determined that p-menthane monoterpenoids in Pelargonium are likely synthesized from (+)-limonene via (+)-piperitone rather than (+)-pulegone. Exploitation of this natural population enabled a detailed dissection of the relative rates of competing p-menthane and citronelloid pathways in this species, providing real time rates of monoterpene accumulation in glandular trichomes." @default.
- W2970805220 created "2019-09-05" @default.
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- W2970805220 date "2019-08-31" @default.
- W2970805220 modified "2023-10-12" @default.
- W2970805220 title "Distinct metabolic pathways drive monoterpenoid biosynthesis in a natural population of Pelargonium graveolens" @default.
- W2970805220 cites W143799972 @default.
- W2970805220 cites W1535671443 @default.
- W2970805220 cites W156408297 @default.
- W2970805220 cites W1771573809 @default.
- W2970805220 cites W183468916 @default.
- W2970805220 cites W1857603706 @default.
- W2970805220 cites W1864140401 @default.
- W2970805220 cites W193022018 @default.
- W2970805220 cites W1965853460 @default.
- W2970805220 cites W1966481718 @default.
- W2970805220 cites W1966609513 @default.
- W2970805220 cites W1975261480 @default.
- W2970805220 cites W1975422418 @default.
- W2970805220 cites W1976327004 @default.
- W2970805220 cites W1977728922 @default.
- W2970805220 cites W1978121850 @default.
- W2970805220 cites W1983879496 @default.
- W2970805220 cites W1984650309 @default.
- W2970805220 cites W1986625944 @default.
- W2970805220 cites W1988734079 @default.
- W2970805220 cites W1993639000 @default.
- W2970805220 cites W1994141255 @default.
- W2970805220 cites W1994575735 @default.
- W2970805220 cites W1994901455 @default.
- W2970805220 cites W2001532982 @default.
- W2970805220 cites W2004603637 @default.
- W2970805220 cites W2008748383 @default.
- W2970805220 cites W2011472416 @default.
- W2970805220 cites W2012605209 @default.
- W2970805220 cites W2022061496 @default.
- W2970805220 cites W2023279198 @default.
- W2970805220 cites W2026127168 @default.
- W2970805220 cites W2037827934 @default.
- W2970805220 cites W2040878176 @default.
- W2970805220 cites W2043165163 @default.
- W2970805220 cites W2056480119 @default.
- W2970805220 cites W2059051661 @default.
- W2970805220 cites W2070080783 @default.
- W2970805220 cites W2082537938 @default.
- W2970805220 cites W2083150532 @default.
- W2970805220 cites W2094422682 @default.
- W2970805220 cites W2105916568 @default.
- W2970805220 cites W2111550864 @default.
- W2970805220 cites W2112153867 @default.
- W2970805220 cites W2113410899 @default.
- W2970805220 cites W2113824190 @default.
- W2970805220 cites W2117651089 @default.
- W2970805220 cites W2125149319 @default.
- W2970805220 cites W2137111266 @default.
- W2970805220 cites W2138695301 @default.
- W2970805220 cites W2138939726 @default.
- W2970805220 cites W2151393496 @default.
- W2970805220 cites W2152512615 @default.
- W2970805220 cites W2153758279 @default.
- W2970805220 cites W2158282833 @default.
- W2970805220 cites W2161030582 @default.
- W2970805220 cites W2161140383 @default.
- W2970805220 cites W2161736228 @default.
- W2970805220 cites W2168263315 @default.
- W2970805220 cites W2170285648 @default.
- W2970805220 cites W2205700517 @default.
- W2970805220 cites W2268080158 @default.
- W2970805220 cites W2475167950 @default.
- W2970805220 cites W2563717514 @default.
- W2970805220 cites W2567591159 @default.
- W2970805220 cites W2588311143 @default.
- W2970805220 cites W2601071569 @default.
- W2970805220 cites W2607292053 @default.
- W2970805220 cites W2759119351 @default.
- W2970805220 cites W2766946295 @default.
- W2970805220 cites W2775150863 @default.
- W2970805220 cites W2803664483 @default.
- W2970805220 cites W2889969755 @default.
- W2970805220 cites W4250095211 @default.
- W2970805220 cites W4254687493 @default.
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- W2970805220 doi "https://doi.org/10.1093/jxb/erz397" @default.
- W2970805220 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6913739" @default.
- W2970805220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31504760" @default.
- W2970805220 hasPublicationYear "2019" @default.
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