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• W2970858049 endingPage "103405" @default.
• W2970858049 startingPage "103405" @default.
• W2970858049 abstract "Lack of wet adhesion and biomechanical mismatch at tissue interfaces are the major challenges related to surgical adhesive formulations. Carbene-based bioadhesives seek to address those limitations, due to their ability to covalently bond to wet tissue surfaces. Herein, diazirine-grafted polyamidoamine (PAMAM) dendrimers (PDz) dissolved in various liquid polyethylene glycols (PEG) are reported. Non-aqueous liquid PEG 400 reinforced with high molecular weight PEGs (2 kDa, 6 kDA and 10 kDa) dissolved PDz to form tertiary blends for optimization of viscosity and shear storage modulus. Dynamic photorheometry correlated PEG molar mass and tertiary ratios to adhesion strength, swelling-in-water profile and potential weight loss in aqueous medium. Tertiary blended adhesives demonstrate an improvement in elongation and adhesion strength compared to the binary blends used as control." @default.
• W2970858049 created "2019-09-05" @default.
• W2970858049 creator A5024671621 @default.
• W2970858049 creator A5047138699 @default.
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• W2970858049 date "2020-01-01" @default.
• W2970858049 modified "2023-10-15" @default.
• W2970858049 title "Tertiary blends of PAMAM/PEG/PEG tissue bioadhesives" @default.
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• W2970858049 doi "https://doi.org/10.1016/j.jmbbm.2019.103405" @default.
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• W2970858049 hasPublicationYear "2020" @default.
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