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- W2970859273 abstract "Background and aims Paracetamol and non-steroidal anti-inflammatory drugs (e.g. ketorolac) can be considered for mild to moderate post-caesarean pain. as a selective α-2 agonist adrenergic receptor, dexmedetomidine has analgesic and sedative effects without causing respiratory depression. This study aimed to evaluate the effects of adding dexmedetomidine to paracetamol or ketorolac on post-caesarean pain and the associated complications thereof. Methods 60 pregnant women who were candidates for caesarean section with spinal anesthesia were randomly assigned to either of two groups of 30 patients. For post-operative pain management, an intravenous patient-controlled analgesia (PCA) device was used for 24 hours. Dexmedetomidine (3 µg kg-1) was added to paracetamol (35 mg kg-1) in the group DP and to ketorolac (1 mg kg-1) in the group DK. Visual analog scale (VAS), Ramsay sedation scale, hemodynamic changes, rescue analgesic (meperidine) consumption, patient satisfaction, and possible complications were recorded at 6, 12, and 24, hours after surgery, and compared afterward. Results The pain score was significantly lower in the DK group than in the DP group (P Conclusions The addition of dexmedetomidine to ketorolac, compared with its addition to paracetamol, causes further reduction in the post-operative pain score and provides more satisfaction." @default.
- W2970859273 created "2019-09-05" @default.
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- W2970859273 date "2019-08-30" @default.
- W2970859273 modified "2023-09-27" @default.
- W2970859273 title "ESRA19-0576 Comparison of the post-caesarean analgesic effects of adding dexmedetomidine to paracetamol and ketorolac" @default.
- W2970859273 doi "https://doi.org/10.1136/rapm-2019-esraabs2019.145" @default.
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