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- W2970907955 abstract "The rapidly expanding field of tissue engineering along with stem cell therapy has a promising future in pediatric urological conditions. The initial struggle seemed difficult in renal regeneration but a functional biounit has been developed. Urine excretion has been demonstrated successfully from stem cell-generated embryonic kidneys. Three-dimensional (3D) stem cell-derived organoids are the new paradigm in research. Techniques to regenerate bladder tissue have reached the clinic, and the urethra is close behind. 3D bioprinted urethras would soon be available. Artificial germ cells produced from mouse pluripotent stem cells have been shown to give rise to live progeny. Myoblast and fibroblast therapy has been safely and effectively used for urinary incontinence. Stress urinary incontinence has been clinically treated with muscle-derived stem cells. Skeletal muscle-derived stem cells have been shown to get converted into smooth muscle cells when implanted into the corpora cavernosa in animal models. This review encompasses the various experimental and clinical developments in this field that can benefit pediatric urological conditions with the contemporary developments in the field." @default.
- W2970907955 created "2019-09-05" @default.
- W2970907955 creator A5020155071 @default.
- W2970907955 creator A5079476385 @default.
- W2970907955 date "2019-01-01" @default.
- W2970907955 modified "2023-10-15" @default.
- W2970907955 title "Tissue engineering and stem cell therapy in pediatric urology" @default.
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- W2970907955 doi "https://doi.org/10.4103/jiaps.jiaps_77_18" @default.
- W2970907955 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6752070" @default.
- W2970907955 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31571753" @default.
- W2970907955 hasPublicationYear "2019" @default.
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