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- W2971174433 abstract "Osteoporosis is a medical condition in which bone becomes fragile and weak. In this condition, the quality and density of the bone are reduced. Vitamin K is vital for bone mineralization as it plays a vital role in the gamma-carboxylation of osteocalcin. Therefore, if there is a deficiency of vitamin K, it can lead to osteoporosis due to undercarboxylated osteocalcin. Warfarin is the most widely used anticoagulant in the elderly. In this article, we reviewed how Warfarin, an inhibitor of vitamin K, affects bone remodeling and leads to osteoporosis." @default.
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- W2971174433 date "2019-08-28" @default.
- W2971174433 modified "2023-10-16" @default.
- W2971174433 title "Drug-induced Reduction of Gamma Carboxylation in Osteocalcin: What is the Fallback?" @default.
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- W2971174433 doi "https://doi.org/10.7759/cureus.5504" @default.
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