Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971252340> ?p ?o ?g. }
- W2971252340 endingPage "100774" @default.
- W2971252340 startingPage "100774" @default.
- W2971252340 abstract "Quantitative fundus autofluorescence (qAF) is an approach that is built on a confocal scanning laser platform and used to measure the intensity of the inherent autofluorescence of retina elicited by short-wavelength (488 nm) excitation. Being non-invasive, qAF does not interrupt tissue architecture, thus allowing for structural correlations. The spectral features, cellular origin and topographic distribution of the natural autofluorescence of the fundus indicate that it is emitted from retinaldehyde-adducts that form in photoreceptor cells and accumulate, under most conditions, in retinal pigment epithelial cells. The distributions and intensities of fundus autofluorescence deviate from normal in many retinal disorders and it is widely recognized that these changing patterns can aid in the diagnosis and monitoring of retinal disease. The standardized protocol employed by qAF involves the normalization of fundus grey levels to a fluorescent reference installed in the imaging instrument. Together with corrections for magnification and anterior media absorption, this approach facilitates comparisons with serial images and images acquired within groups of patients. Here we provide a comprehensive summary of the principles and practice of qAF and we highlight recent efforts to elucidate retinal disease processes by combining qAF with multi-modal imaging." @default.
- W2971252340 created "2019-09-05" @default.
- W2971252340 creator A5008909472 @default.
- W2971252340 creator A5052522656 @default.
- W2971252340 creator A5056018713 @default.
- W2971252340 creator A5057464344 @default.
- W2971252340 creator A5064040263 @default.
- W2971252340 date "2020-01-01" @default.
- W2971252340 modified "2023-10-01" @default.
- W2971252340 title "Lessons learned from quantitative fundus autofluorescence" @default.
- W2971252340 cites W1501706589 @default.
- W2971252340 cites W1521915926 @default.
- W2971252340 cites W1541138555 @default.
- W2971252340 cites W1602482210 @default.
- W2971252340 cites W1719249858 @default.
- W2971252340 cites W1803904511 @default.
- W2971252340 cites W1963636120 @default.
- W2971252340 cites W1963749123 @default.
- W2971252340 cites W1964290025 @default.
- W2971252340 cites W1964753793 @default.
- W2971252340 cites W1965144327 @default.
- W2971252340 cites W1966039514 @default.
- W2971252340 cites W1967034717 @default.
- W2971252340 cites W1970859316 @default.
- W2971252340 cites W1972258703 @default.
- W2971252340 cites W1974626059 @default.
- W2971252340 cites W1976016385 @default.
- W2971252340 cites W1977736972 @default.
- W2971252340 cites W1979029890 @default.
- W2971252340 cites W1982740394 @default.
- W2971252340 cites W1987669878 @default.
- W2971252340 cites W1988449174 @default.
- W2971252340 cites W1988592497 @default.
- W2971252340 cites W1989574886 @default.
- W2971252340 cites W1990257468 @default.
- W2971252340 cites W1992364186 @default.
- W2971252340 cites W1992530885 @default.
- W2971252340 cites W1992885426 @default.
- W2971252340 cites W1994172606 @default.
- W2971252340 cites W1995270215 @default.
- W2971252340 cites W1995818991 @default.
- W2971252340 cites W1995949600 @default.
- W2971252340 cites W1997371384 @default.
- W2971252340 cites W1997925124 @default.
- W2971252340 cites W2001232102 @default.
- W2971252340 cites W2001271130 @default.
- W2971252340 cites W2002714238 @default.
- W2971252340 cites W2002986171 @default.
- W2971252340 cites W2006688063 @default.
- W2971252340 cites W2007551900 @default.
- W2971252340 cites W2007969062 @default.
- W2971252340 cites W2009159665 @default.
- W2971252340 cites W2009738449 @default.
- W2971252340 cites W2015046077 @default.
- W2971252340 cites W2015072257 @default.
- W2971252340 cites W2015153021 @default.
- W2971252340 cites W2015540555 @default.
- W2971252340 cites W2015931829 @default.
- W2971252340 cites W2016410640 @default.
- W2971252340 cites W2018327654 @default.
- W2971252340 cites W2019731198 @default.
- W2971252340 cites W2021594640 @default.
- W2971252340 cites W2022312877 @default.
- W2971252340 cites W2022817398 @default.
- W2971252340 cites W2023056992 @default.
- W2971252340 cites W2023768917 @default.
- W2971252340 cites W2024400576 @default.
- W2971252340 cites W2025859292 @default.
- W2971252340 cites W2027806625 @default.
- W2971252340 cites W2028221037 @default.
- W2971252340 cites W2038140902 @default.
- W2971252340 cites W2038203767 @default.
- W2971252340 cites W2038659009 @default.
- W2971252340 cites W2042158806 @default.
- W2971252340 cites W2046608494 @default.
- W2971252340 cites W2046761602 @default.
- W2971252340 cites W2048505879 @default.
- W2971252340 cites W2049833320 @default.
- W2971252340 cites W2054279811 @default.
- W2971252340 cites W2059022308 @default.
- W2971252340 cites W2060448170 @default.
- W2971252340 cites W2061758705 @default.
- W2971252340 cites W2066822048 @default.
- W2971252340 cites W2068607898 @default.
- W2971252340 cites W2071088429 @default.
- W2971252340 cites W2071360337 @default.
- W2971252340 cites W2073522690 @default.
- W2971252340 cites W2073969162 @default.
- W2971252340 cites W2077069863 @default.
- W2971252340 cites W2077828041 @default.
- W2971252340 cites W2078313942 @default.
- W2971252340 cites W2079787990 @default.
- W2971252340 cites W2081383973 @default.
- W2971252340 cites W2082541003 @default.
- W2971252340 cites W2082659516 @default.
- W2971252340 cites W2083242977 @default.
- W2971252340 cites W2086257051 @default.
- W2971252340 cites W2088740316 @default.