FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971304551> ?p ?o ?g. }

• W2971304551 endingPage "107" @default.
• W2971304551 startingPage "92" @default.
• W2971304551 abstract "No network meta-analysis has examined the relative effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression, while this is a very important clinical issue. We conducted systematic searches in bibliographical databases to identify randomized trials in which a psychotherapy and a pharmacotherapy for the acute or long-term treatment of depression were compared with each other, or in which the combination of a psychotherapy and a pharmacotherapy was compared with either one alone. The main outcome was treatment response (50% improvement between baseline and endpoint). Remission and acceptability (defined as study drop-out for any reason) were also examined. Possible moderators that were assessed included chronic and treatment-resistant depression and baseline severity of depression. Data were pooled as relative risk (RR) using a random-effects model. A total of 101 studies with 11,910 patients were included. Depression in most studies was moderate to severe. In the network meta-analysis, combined treatment was more effective than psychotherapy alone (RR=1.27; 95% CI: 1.14-1.39) and pharmacotherapy alone (RR=1.25; 95% CI: 1.14-1.37) in achieving response at the end of treatment. No significant difference was found between psychotherapy alone and pharmacotherapy alone (RR=0.99; 95% CI: 0.92-1.08). Similar results were found for remission. Combined treatment (RR=1.23; 95% CI: 1.05-1.45) and psychotherapy alone (RR=1.17; 95% CI: 1.02-1.32) were more acceptable than pharmacotherapy. Results were similar for chronic and treatment-resistant depression. The combination of psychotherapy and pharmacotherapy seems to be the best choice for patients with moderate depression. More research is needed on long-term effects of treatments (including cost-effectiveness), on the impact of specific pharmacological and non-pharmacological approaches, and on the effects in specific populations of patients." @default.
• W2971304551 created "2019-09-05" @default.
• W2971304551 creator A5007077090 @default.
• W2971304551 creator A5016972944 @default.
• W2971304551 creator A5032982998 @default.
• W2971304551 creator A5063320082 @default.
• W2971304551 creator A5084041690 @default.
• W2971304551 creator A5085050194 @default.
• W2971304551 date "2020-01-10" @default.
• W2971304551 modified "2023-10-10" @default.
• W2971304551 title "A network meta‐analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression" @default.
• W2971304551 cites W121628122 @default.
• W2971304551 cites W123996836 @default.
• W2971304551 cites W135319519 @default.
• W2971304551 cites W1474740825 @default.
• W2971304551 cites W1499844489 @default.
• W2971304551 cites W1507684176 @default.
• W2971304551 cites W1543626199 @default.
• W2971304551 cites W1588934057 @default.
• W2971304551 cites W1840158357 @default.
• W2971304551 cites W1859374672 @default.
• W2971304551 cites W1882389957 @default.
• W2971304551 cites W1930885864 @default.
• W2971304551 cites W1964157514 @default.
• W2971304551 cites W1975972867 @default.
• W2971304551 cites W1976615687 @default.
• W2971304551 cites W1978560738 @default.
• W2971304551 cites W1980335974 @default.
• W2971304551 cites W1995972496 @default.
• W2971304551 cites W2001307836 @default.
• W2971304551 cites W2006140169 @default.
• W2971304551 cites W2006748124 @default.
• W2971304551 cites W2008044072 @default.
• W2971304551 cites W2012842009 @default.
• W2971304551 cites W2013871251 @default.
• W2971304551 cites W2015006744 @default.
• W2971304551 cites W2016222915 @default.
• W2971304551 cites W2017459421 @default.
• W2971304551 cites W2019471869 @default.
• W2971304551 cites W2019576451 @default.
• W2971304551 cites W2020279836 @default.
• W2971304551 cites W2028940268 @default.
• W2971304551 cites W2032583580 @default.
• W2971304551 cites W2033139495 @default.
• W2971304551 cites W2033212262 @default.
• W2971304551 cites W2037671669 @default.
• W2971304551 cites W2038407026 @default.
• W2971304551 cites W2038701603 @default.
• W2971304551 cites W2040664278 @default.
• W2971304551 cites W2043866203 @default.
• W2971304551 cites W2048087221 @default.
• W2971304551 cites W2048342733 @default.
• W2971304551 cites W2048939963 @default.
• W2971304551 cites W2052779111 @default.
• W2971304551 cites W2053011811 @default.
• W2971304551 cites W2053964227 @default.
• W2971304551 cites W2056471444 @default.
• W2971304551 cites W2056640167 @default.
• W2971304551 cites W2057699322 @default.
• W2971304551 cites W2057813824 @default.
• W2971304551 cites W2058760081 @default.
• W2971304551 cites W2062430362 @default.
• W2971304551 cites W2064448301 @default.
• W2971304551 cites W2066146596 @default.
• W2971304551 cites W2069601200 @default.
• W2971304551 cites W2071104598 @default.
• W2971304551 cites W2072273713 @default.
• W2971304551 cites W2081302185 @default.
• W2971304551 cites W2083877757 @default.
• W2971304551 cites W2084315798 @default.
• W2971304551 cites W2085803274 @default.
• W2971304551 cites W2085805157 @default.
• W2971304551 cites W2090588535 @default.
• W2971304551 cites W2091808438 @default.
• W2971304551 cites W2091899813 @default.
• W2971304551 cites W2091915974 @default.
• W2971304551 cites W2092686956 @default.
• W2971304551 cites W2093842732 @default.
• W2971304551 cites W2096684104 @default.
• W2971304551 cites W2097633023 @default.
• W2971304551 cites W2098923148 @default.
• W2971304551 cites W2100490307 @default.
• W2971304551 cites W2101681930 @default.
• W2971304551 cites W2105669432 @default.
• W2971304551 cites W2107921915 @default.
• W2971304551 cites W2113302965 @default.
• W2971304551 cites W2113921657 @default.
• W2971304551 cites W2114536224 @default.
• W2971304551 cites W2114613490 @default.
• W2971304551 cites W2117994084 @default.
• W2971304551 cites W2118138493 @default.
• W2971304551 cites W2118772250 @default.
• W2971304551 cites W2119475075 @default.
• W2971304551 cites W2122365164 @default.
• W2971304551 cites W2122432644 @default.
• W2971304551 cites W2128913569 @default.
• W2971304551 cites W2129821518 @default.
• W2971304551 cites W2130481569 @default.

• next