Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971308982> ?p ?o ?g. }
- W2971308982 endingPage "43" @default.
- W2971308982 startingPage "43" @default.
- W2971308982 abstract "To assess the role of p63, a p53 homolog, in the cytodifferentiation (odontogenesis) and oncogenesis of odontogenic epithelium.The present study aimed to compare the expression pattern of p63 in the epithelium of tooth germ, dentigerous cyst (DC) and ameloblastoma (AB).Tissue specimens of thirty tooth germs, thirty ABs and thirty DCs were examined by immunohistochemistry for the expression of p63. Results: p63 labeling index (LI) was observed in descending order in epithelial cells of ABs, tooth germs and DCs. p63 LI was statistically nonsignificant among all the three groups. ABs revealed the highest p63 expression, but, surprisingly, tooth germs showed higher expression than DCs.p63 plays a role in the cytodifferentiation and proliferation of odontogenic epithelial cells irrespective of the tissue (normal developing or lesional tissue). This implies that p63 cannot be used as a diagnostic marker. However, our results indicate p63 overexpression as a mark of increased proliferation. Thus, it can be stipulated that p63 can be used as a prognostic marker in odontogenic lesions with more aggressive and invasive phenotype. Our results also suggest the differential function of p63 in both developing and lesional odontogenic tissues, which, however, depends on p63 isoform predominantly being expressed. Therefore, identification of p63-predominant isoform in a particular lesion is more important than the presence or absence of p63. Consequently, we suggest the performance of polymerase chain reaction analysis along with immunohistochemical evaluation in further studies." @default.
- W2971308982 created "2019-09-05" @default.
- W2971308982 creator A5025507503 @default.
- W2971308982 creator A5043611903 @default.
- W2971308982 creator A5046220892 @default.
- W2971308982 creator A5056884356 @default.
- W2971308982 creator A5063397672 @default.
- W2971308982 creator A5085329008 @default.
- W2971308982 date "2019-01-01" @default.
- W2971308982 modified "2023-10-05" @default.
- W2971308982 title "Expression of p63 in tooth germ, dentigerous cyst and ameloblastoma" @default.
- W2971308982 cites W1985064409 @default.
- W2971308982 cites W1992916646 @default.
- W2971308982 cites W1995995906 @default.
- W2971308982 cites W1997204516 @default.
- W2971308982 cites W2004965467 @default.
- W2971308982 cites W2014938226 @default.
- W2971308982 cites W2039527683 @default.
- W2971308982 cites W2043406735 @default.
- W2971308982 cites W2047755022 @default.
- W2971308982 cites W2052263492 @default.
- W2971308982 cites W2054273558 @default.
- W2971308982 cites W2054549064 @default.
- W2971308982 cites W2060823106 @default.
- W2971308982 cites W2062364714 @default.
- W2971308982 cites W2078087720 @default.
- W2971308982 cites W2083746931 @default.
- W2971308982 cites W2091189326 @default.
- W2971308982 cites W2104660225 @default.
- W2971308982 cites W2105087414 @default.
- W2971308982 cites W2114173985 @default.
- W2971308982 cites W2124818286 @default.
- W2971308982 cites W2135927454 @default.
- W2971308982 cites W2147724452 @default.
- W2971308982 cites W2152488609 @default.
- W2971308982 cites W2156192201 @default.
- W2971308982 cites W2163565167 @default.
- W2971308982 doi "https://doi.org/10.4103/jomfp.jomfp_125_18" @default.
- W2971308982 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6503805" @default.
- W2971308982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31110415" @default.
- W2971308982 hasPublicationYear "2019" @default.
- W2971308982 type Work @default.
- W2971308982 sameAs 2971308982 @default.
- W2971308982 citedByCount "5" @default.
- W2971308982 countsByYear W29713089822023 @default.
- W2971308982 crossrefType "journal-article" @default.
- W2971308982 hasAuthorship W2971308982A5025507503 @default.
- W2971308982 hasAuthorship W2971308982A5043611903 @default.
- W2971308982 hasAuthorship W2971308982A5046220892 @default.
- W2971308982 hasAuthorship W2971308982A5056884356 @default.
- W2971308982 hasAuthorship W2971308982A5063397672 @default.
- W2971308982 hasAuthorship W2971308982A5085329008 @default.
- W2971308982 hasConcept C104317684 @default.
- W2971308982 hasConcept C105702510 @default.
- W2971308982 hasConcept C122246415 @default.
- W2971308982 hasConcept C127716648 @default.
- W2971308982 hasConcept C142724271 @default.
- W2971308982 hasConcept C204232928 @default.
- W2971308982 hasConcept C2775876115 @default.
- W2971308982 hasConcept C2777610189 @default.
- W2971308982 hasConcept C2780597408 @default.
- W2971308982 hasConcept C2780856748 @default.
- W2971308982 hasConcept C2781156865 @default.
- W2971308982 hasConcept C529295009 @default.
- W2971308982 hasConcept C54355233 @default.
- W2971308982 hasConcept C555283112 @default.
- W2971308982 hasConcept C71924100 @default.
- W2971308982 hasConcept C86803240 @default.
- W2971308982 hasConceptScore W2971308982C104317684 @default.
- W2971308982 hasConceptScore W2971308982C105702510 @default.
- W2971308982 hasConceptScore W2971308982C122246415 @default.
- W2971308982 hasConceptScore W2971308982C127716648 @default.
- W2971308982 hasConceptScore W2971308982C142724271 @default.
- W2971308982 hasConceptScore W2971308982C204232928 @default.
- W2971308982 hasConceptScore W2971308982C2775876115 @default.
- W2971308982 hasConceptScore W2971308982C2777610189 @default.
- W2971308982 hasConceptScore W2971308982C2780597408 @default.
- W2971308982 hasConceptScore W2971308982C2780856748 @default.
- W2971308982 hasConceptScore W2971308982C2781156865 @default.
- W2971308982 hasConceptScore W2971308982C529295009 @default.
- W2971308982 hasConceptScore W2971308982C54355233 @default.
- W2971308982 hasConceptScore W2971308982C555283112 @default.
- W2971308982 hasConceptScore W2971308982C71924100 @default.
- W2971308982 hasConceptScore W2971308982C86803240 @default.
- W2971308982 hasIssue "1" @default.
- W2971308982 hasLocation W29713089821 @default.
- W2971308982 hasLocation W29713089822 @default.
- W2971308982 hasOpenAccess W2971308982 @default.
- W2971308982 hasPrimaryLocation W29713089821 @default.
- W2971308982 hasRelatedWork W1486367141 @default.
- W2971308982 hasRelatedWork W1925811005 @default.
- W2971308982 hasRelatedWork W1972210157 @default.
- W2971308982 hasRelatedWork W2017915703 @default.
- W2971308982 hasRelatedWork W2062236443 @default.
- W2971308982 hasRelatedWork W2615112294 @default.
- W2971308982 hasRelatedWork W3005824775 @default.
- W2971308982 hasRelatedWork W3009648814 @default.
- W2971308982 hasRelatedWork W3111095045 @default.