Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971336609> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2971336609 endingPage "108" @default.
- W2971336609 startingPage "100" @default.
- W2971336609 abstract "The purpose of this study is to explore the function and regulatory networks of differentially expressed genes (DEGs) in head and neck squamous cell carcinoma (HNSC) by bioinformatics analysis using bioinformatics methods. The gene expression profile associated with HNSC was upregulated from the Cancer RNA-Seq Nexus (CRN) database and Oncomine. Functional analysis of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and gene ontology was performed on DEGs. The protein–protein interaction (PPI) network of DEGs was constructed using STRING and Cytoscape databases. A PPI network contained 101 genes. According to the comprehensive analysis of Degree and MCODE score, there are 12 genes. Based on the screened protein network and differential genes, further exploration was conducted according to The Cancer Genome Atlas (TCGA) normal and the genotype-tissue expression (GTEx) data. This investigation involved observing the expression of the first eight hub genes in tissues and the expression of NIMA-related kinase 2 (NEK2) in different stages and then survival analysis of HNSC. Results showed that NEK2 has important value in HNSC, which provides a reference for the molecular mechanism of HNSC." @default.
- W2971336609 created "2019-09-05" @default.
- W2971336609 creator A5043126936 @default.
- W2971336609 creator A5050776813 @default.
- W2971336609 creator A5084075408 @default.
- W2971336609 date "2020-01-01" @default.
- W2971336609 modified "2023-09-24" @default.
- W2971336609 title "Integrative Bioinformatics Analysis Identifies NEK2 as a Potential Biomarker in Head and Neck Squamous Cell Carcinoma" @default.
- W2971336609 cites W1943154073 @default.
- W2971336609 cites W1984596305 @default.
- W2971336609 cites W2001107815 @default.
- W2971336609 cites W2041949509 @default.
- W2971336609 cites W2044433401 @default.
- W2971336609 cites W2124268899 @default.
- W2971336609 cites W2137012880 @default.
- W2971336609 cites W2141274038 @default.
- W2971336609 cites W2288223381 @default.
- W2971336609 cites W2531927615 @default.
- W2971336609 cites W2578625798 @default.
- W2971336609 cites W2606428688 @default.
- W2971336609 cites W2608913686 @default.
- W2971336609 cites W2614488762 @default.
- W2971336609 cites W2616692187 @default.
- W2971336609 cites W2622179910 @default.
- W2971336609 cites W2738257363 @default.
- W2971336609 cites W2755696548 @default.
- W2971336609 cites W2768310080 @default.
- W2971336609 cites W2783690443 @default.
- W2971336609 cites W2790774242 @default.
- W2971336609 cites W2803606292 @default.
- W2971336609 cites W2804177971 @default.
- W2971336609 cites W2886977572 @default.
- W2971336609 cites W2888530271 @default.
- W2971336609 cites W2890133814 @default.
- W2971336609 cites W2890221295 @default.
- W2971336609 cites W2896197414 @default.
- W2971336609 cites W2896899565 @default.
- W2971336609 cites W2900612680 @default.
- W2971336609 cites W2907538574 @default.
- W2971336609 cites W2919413784 @default.
- W2971336609 doi "https://doi.org/10.1089/cmb.2019.0208" @default.
- W2971336609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31460782" @default.
- W2971336609 hasPublicationYear "2020" @default.
- W2971336609 type Work @default.
- W2971336609 sameAs 2971336609 @default.
- W2971336609 citedByCount "5" @default.
- W2971336609 countsByYear W29713366092021 @default.
- W2971336609 countsByYear W29713366092022 @default.
- W2971336609 countsByYear W29713366092023 @default.
- W2971336609 crossrefType "journal-article" @default.
- W2971336609 hasAuthorship W2971336609A5043126936 @default.
- W2971336609 hasAuthorship W2971336609A5050776813 @default.
- W2971336609 hasAuthorship W2971336609A5084075408 @default.
- W2971336609 hasConcept C104317684 @default.
- W2971336609 hasConcept C121608353 @default.
- W2971336609 hasConcept C150194340 @default.
- W2971336609 hasConcept C152724338 @default.
- W2971336609 hasConcept C158163496 @default.
- W2971336609 hasConcept C2776530083 @default.
- W2971336609 hasConcept C2776833033 @default.
- W2971336609 hasConcept C2987395477 @default.
- W2971336609 hasConcept C54355233 @default.
- W2971336609 hasConcept C60644358 @default.
- W2971336609 hasConcept C6856738 @default.
- W2971336609 hasConcept C70721500 @default.
- W2971336609 hasConcept C86803240 @default.
- W2971336609 hasConceptScore W2971336609C104317684 @default.
- W2971336609 hasConceptScore W2971336609C121608353 @default.
- W2971336609 hasConceptScore W2971336609C150194340 @default.
- W2971336609 hasConceptScore W2971336609C152724338 @default.
- W2971336609 hasConceptScore W2971336609C158163496 @default.
- W2971336609 hasConceptScore W2971336609C2776530083 @default.
- W2971336609 hasConceptScore W2971336609C2776833033 @default.
- W2971336609 hasConceptScore W2971336609C2987395477 @default.
- W2971336609 hasConceptScore W2971336609C54355233 @default.
- W2971336609 hasConceptScore W2971336609C60644358 @default.
- W2971336609 hasConceptScore W2971336609C6856738 @default.
- W2971336609 hasConceptScore W2971336609C70721500 @default.
- W2971336609 hasConceptScore W2971336609C86803240 @default.
- W2971336609 hasIssue "1" @default.
- W2971336609 hasLocation W29713366091 @default.
- W2971336609 hasOpenAccess W2971336609 @default.
- W2971336609 hasPrimaryLocation W29713366091 @default.
- W2971336609 hasRelatedWork W2009966535 @default.
- W2971336609 hasRelatedWork W2513743670 @default.
- W2971336609 hasRelatedWork W2748644580 @default.
- W2971336609 hasRelatedWork W2909382709 @default.
- W2971336609 hasRelatedWork W3010880597 @default.
- W2971336609 hasRelatedWork W3127907745 @default.
- W2971336609 hasRelatedWork W3200763748 @default.
- W2971336609 hasRelatedWork W4205963003 @default.
- W2971336609 hasRelatedWork W4285535790 @default.
- W2971336609 hasRelatedWork W4385334780 @default.
- W2971336609 hasVolume "27" @default.
- W2971336609 isParatext "false" @default.
- W2971336609 isRetracted "false" @default.
- W2971336609 magId "2971336609" @default.
- W2971336609 workType "article" @default.