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• W2971337732 endingPage "112188" @default.
• W2971337732 startingPage "112188" @default.
• W2971337732 abstract "Healthy animals displaying extreme behaviours that resemble human psychiatric symptoms are relevant models to study the natural psychobiological processes of maladapted behaviours. Using a Rat Gambling Task, healthy individuals spontaneously making poor decisions (PDMs) were found to co-express a combination of other cognitive and reward-based characteristics similar to symptoms observed in human patients with impulse-control disorders. The main goals of this study were to 1) confirm the existence of PDMs and their unique behavioural phenotypes in Dark Agouti (DA) and Wistar Han (WH) rats, 2) to extend the behavioural profile of the PDMs to probability-based decision-making and social behaviours and 3) to extract key discriminative traits between DA and WH strains, relevant for biomedical research. We have compared cognitive abilities, natural behaviours and physiological responses in DA and WH rats at the strain and at the individual level. Here we found that the naturally occurring PDM’s profile was consistent between both rat lines. Then, although the PDM individuals did not take more risks in probability discounting task, they seemed to be of higher social ranks. Finally and despite their similarities in performance, WH and DA lines differed in degree of reward sensitivity, impulsivity, locomotor activity and open space-occupation. The reproducibility and conservation of the complex phenotypes of PDMs and GDMs (good decision makers) in these two genetically different strains support their translational potential. Both strains, present large phenotypic variation in behaviours pertinent for the study of the underlying mechanisms of poor decision making and associated disorders." @default.
• W2971337732 created "2019-09-05" @default.
• W2971337732 creator A5003480680 @default.
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• W2971337732 creator A5059936166 @default.
• W2971337732 creator A5089655742 @default.
• W2971337732 date "2020-01-01" @default.
• W2971337732 modified "2023-10-16" @default.
• W2971337732 title "Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats" @default.
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• W2971337732 cites W1852628838 @default.
• W2971337732 cites W1895018411 @default.
• W2971337732 cites W1934200177 @default.
• W2971337732 cites W1971659939 @default.
• W2971337732 cites W1974378661 @default.
• W2971337732 cites W1975710591 @default.
• W2971337732 cites W1977465442 @default.
• W2971337732 cites W1985052963 @default.
• W2971337732 cites W1990580330 @default.
• W2971337732 cites W1992052818 @default.
• W2971337732 cites W1998247620 @default.
• W2971337732 cites W2007816528 @default.
• W2971337732 cites W2010818484 @default.
• W2971337732 cites W2011027148 @default.
• W2971337732 cites W2017275629 @default.
• W2971337732 cites W2017604238 @default.
• W2971337732 cites W2017609232 @default.
• W2971337732 cites W2021060120 @default.
• W2971337732 cites W2021190392 @default.
• W2971337732 cites W2029397851 @default.
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• W2971337732 cites W2034531314 @default.
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• W2971337732 cites W2044374996 @default.
• W2971337732 cites W2049684848 @default.
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• W2971337732 cites W2056279061 @default.
• W2971337732 cites W2057486051 @default.
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• W2971337732 cites W2067509569 @default.
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• W2971337732 cites W2117375834 @default.
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• W2971337732 cites W2119972544 @default.
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• W2971337732 cites W2216317922 @default.
• W2971337732 cites W2412112752 @default.
• W2971337732 cites W2480336835 @default.
• W2971337732 cites W2509878791 @default.
• W2971337732 cites W2530843556 @default.
• W2971337732 cites W2568907917 @default.
• W2971337732 cites W2580492137 @default.
• W2971337732 cites W2603258172 @default.
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• W2971337732 doi "https://doi.org/10.1016/j.bbr.2019.112188" @default.
• W2971337732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31473288" @default.
• W2971337732 hasPublicationYear "2020" @default.
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