FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971383286> ?p ?o ?g. }

• W2971383286 endingPage "1313" @default.
• W2971383286 startingPage "1313" @default.
• W2971383286 abstract "Cancer is a category of diseases involving abnormal cell growth with the potential to invade other parts of the body. Chemotherapy is the most widely used first-line treatment for multiple forms of cancer. Chemotherapeutic agents act via targeting the cellular apoptotic pathway. However, cancer cells usually acquire chemoresistance, leading to poor outcomes in cancer patients. For that reason, it is imperative to discover other cell death pathways for improved cancer intervention. Pyroptosis is a new form of programmed cell death that commonly occurs upon pathogen invasion. Pyroptosis is marked by cell swelling and plasma membrane rupture, which results in the release of cytosolic contents into the extracellular space. Currently, pyroptosis is proposed to be an alternative mode of cell death in cancer treatment. Accumulating evidence shows that the key components of pyroptotic cell death pathways, including inflammasomes, gasdermins and pro-inflammatory cytokines, are involved in the initiation and progression of cancer. Interfering with pyroptotic cell death pathways may represent a promising therapeutic option for cancer management. In this review, we describe the current knowledge regarding the biological significance of pyroptotic cell death pathways in cancer pathogenesis and also discuss their potential therapeutic utility." @default.
• W2971383286 created "2019-09-12" @default.
• W2971383286 creator A5017804963 @default.
• W2971383286 creator A5021202119 @default.
• W2971383286 creator A5030691366 @default.
• W2971383286 creator A5050650769 @default.
• W2971383286 creator A5085934405 @default.
• W2971383286 date "2019-09-05" @default.
• W2971383286 modified "2023-10-12" @default.
• W2971383286 title "The Multifaceted Roles of Pyroptotic Cell Death Pathways in Cancer" @default.
• W2971383286 cites W1539571840 @default.
• W2971383286 cites W1824528611 @default.
• W2971383286 cites W1826663605 @default.
• W2971383286 cites W1864325817 @default.
• W2971383286 cites W1882905539 @default.
• W2971383286 cites W1904683780 @default.
• W2971383286 cites W1964647066 @default.
• W2971383286 cites W1975014158 @default.
• W2971383286 cites W1984026160 @default.
• W2971383286 cites W1985970823 @default.
• W2971383286 cites W1992815676 @default.
• W2971383286 cites W1994711799 @default.
• W2971383286 cites W2001350415 @default.
• W2971383286 cites W2004516435 @default.
• W2971383286 cites W2008581589 @default.
• W2971383286 cites W2009312314 @default.
• W2971383286 cites W2013617327 @default.
• W2971383286 cites W2014602273 @default.
• W2971383286 cites W2014695552 @default.
• W2971383286 cites W2016829809 @default.
• W2971383286 cites W2018758055 @default.
• W2971383286 cites W2020908160 @default.
• W2971383286 cites W2028526690 @default.
• W2971383286 cites W2028893971 @default.
• W2971383286 cites W2032897380 @default.
• W2971383286 cites W2033945320 @default.
• W2971383286 cites W2042816890 @default.
• W2971383286 cites W2042965279 @default.
• W2971383286 cites W2045413385 @default.
• W2971383286 cites W2050798656 @default.
• W2971383286 cites W2055313736 @default.
• W2971383286 cites W2067043938 @default.
• W2971383286 cites W2068619092 @default.
• W2971383286 cites W2070058781 @default.
• W2971383286 cites W2075376076 @default.
• W2971383286 cites W2076071184 @default.
• W2971383286 cites W2078850432 @default.
• W2971383286 cites W2078896740 @default.
• W2971383286 cites W2079882002 @default.
• W2971383286 cites W2080827095 @default.
• W2971383286 cites W2092570035 @default.
• W2971383286 cites W2104414795 @default.
• W2971383286 cites W2107898605 @default.
• W2971383286 cites W2108373994 @default.
• W2971383286 cites W2108827901 @default.
• W2971383286 cites W2113839377 @default.
• W2971383286 cites W2114211513 @default.
• W2971383286 cites W2115347745 @default.
• W2971383286 cites W2117318706 @default.
• W2971383286 cites W2118918019 @default.
• W2971383286 cites W2124335748 @default.
• W2971383286 cites W2128190429 @default.
• W2971383286 cites W2128319428 @default.
• W2971383286 cites W2133924272 @default.
• W2971383286 cites W2134007048 @default.
• W2971383286 cites W2150107812 @default.
• W2971383286 cites W2159321073 @default.
• W2971383286 cites W2169048233 @default.
• W2971383286 cites W2175794645 @default.
• W2971383286 cites W2185402392 @default.
• W2971383286 cites W2198344835 @default.
• W2971383286 cites W2236857445 @default.
• W2971383286 cites W2255169021 @default.
• W2971383286 cites W2265261098 @default.
• W2971383286 cites W2271290641 @default.
• W2971383286 cites W2273759931 @default.
• W2971383286 cites W2280417087 @default.
• W2971383286 cites W2294560320 @default.
• W2971383286 cites W2315509481 @default.
• W2971383286 cites W2324116490 @default.
• W2971383286 cites W2339618580 @default.
• W2971383286 cites W2345334251 @default.
• W2971383286 cites W2400635491 @default.
• W2971383286 cites W2401994568 @default.
• W2971383286 cites W2411678883 @default.
• W2971383286 cites W2418806051 @default.
• W2971383286 cites W2432418760 @default.
• W2971383286 cites W2442963418 @default.
• W2971383286 cites W2460135582 @default.
• W2971383286 cites W2460178156 @default.
• W2971383286 cites W2462773201 @default.
• W2971383286 cites W2464345038 @default.
• W2971383286 cites W2510071623 @default.
• W2971383286 cites W2519666751 @default.
• W2971383286 cites W2521445794 @default.
• W2971383286 cites W2531115813 @default.
• W2971383286 cites W2547429915 @default.
• W2971383286 cites W2551371378 @default.

• next