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• W2971433899 abstract "Abstract Across many studies, ventromedial prefrontal cortex (vmPFC) activity has been found to correlate with subjective value during value-based decision-making. Recently, however, vmPFC has also been shown to reflect a hexagonal gridlike code during navigation through physical and conceptual space. This raises the possibility that the subjective value correlates previously observed in vmPFC may have actually been a misconstrued gridlike signal. Here, we first show that, in theory, a hexagonal gridlike code of two-dimensional attribute space could mimic vmPFC activity previously attributed to subjective value. However, using fMRI data from a large number of subjects performing an intertemporal choice task, we show clear and unambiguous evidence that subjective value is a better description of vmPFC activity than a hexagonal gridlike code. In fact, we find no significant evidence at all for a hexagonal gridlike code in vmPFC activity during intertemporal choice. This result limits the generality of gridlike modulation as description of vmPFC activity. We suggest that vmPFC may flexibly switch representational schemes so as to encode the most relevant information for the current task." @default.
• W2971433899 created "2019-09-12" @default.
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• W2971433899 date "2019-09-08" @default.
• W2971433899 modified "2023-09-23" @default.
• W2971433899 title "Subjective value, not a gridlike code, describes neural activity in ventromedial prefrontal cortex during value-based decision-making" @default.
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• W2971433899 doi "https://doi.org/10.1101/759951" @default.
• W2971433899 hasPublicationYear "2019" @default.
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