Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971469486> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- W2971469486 endingPage "124" @default.
- W2971469486 startingPage "109" @default.
- W2971469486 abstract "Phosphoryl trichloride is a clear, colorless or yellowish liquid with an unpleasant, pungent odor. In contact with water or steam, it rapidly hydrolyses by releasing hydrogen chloride and phosphoric(V) acid. Phosphoryl trichloride is used in industry primarily for the production of alkyl and aryl triesters of phosphoric(V) acid. It is also used in the production of plasticizers, flame retardants, hydraulic fluids, insecticides, pharmaceuticals, gasoline additives and dye intermediates. Phosphoryl trichloride is also used as chlorinating agent, pH regulator, catalyst, solvent in cryoscopy, dopant for semiconductor grade silicon, and as reagent in laboratories. Phosphoryl trichloride is classified for acute toxicity as category 2 with inhalation (inhalation may lead to death) and as category 4 if swallowed (harmful if swallowed). In addition, it is classified as corrosive category 1A (causes severe skin burns and eye damage) and toxic to target organs due to repeated exposure, category 1 (causes damage to organs through prolonged or repeated exposure). Both in acute and chronic cases of inhalation exposure, the primary effect was irritating to the respiratory tract and eyes (burning eyes and throat, feeling of breathlessness, tearing, coughing, bronchospasm, pain behind the sternum, pleurisy). In exposed workers, deterioration of pulmonary spirometric parameters was observed. The late effects of exposure were asthmatic problems and obstructive respiratory disease. Available animal studies are poorly documented. Phosphoryl trichloride did not show any mutagenic effects. There is no information on the carcinogenic, embryotoxic or teratogenic effects of this substance in the available literature. The critical effect of the action of phosphoryl trichloride is a strong irritation on the mucous membranes of the eyes and upper respiratory tract. A concentration of 0.48 mg/m3 constituting the threshold for toxic effects of phosphoryl trichloride in studies in rats and guinea pigs was taken as the LOAEC value. After applying the uncertainty coefficients, the MAC value of phosphoryl trichloride calculated on this basis is 0.06 mg/m3. It is proposed to adopt the MAC value in accordance with the SCOEL and ACSH recommendation, i.e., 0.064 mg/m3. Phosphoryl trichloride is a strongly irritating substance, in order to prevent peak concentrations of this substance it is proposed to set the maximum allowable short-term concentration (MAC-STEL) at level 2 x MAC value, i.e., 0.13 mg/m3. There are no substantive foundations to determine the permissible biological exposure indices to phosphoryl trichloride (DSB). Due to the corrosive effect of phosphoryl chloride, it is proposed to label it with the letter C (a substance with a corrosive effect). This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering." @default.
- W2971469486 created "2019-09-12" @default.
- W2971469486 creator A5053633296 @default.
- W2971469486 creator A5054485607 @default.
- W2971469486 date "2019-09-30" @default.
- W2971469486 modified "2023-09-23" @default.
- W2971469486 title "Phosphoryl trichloride. Documentation of proposed values of occupational exposure limits (OELs)" @default.
- W2971469486 cites W1967335990 @default.
- W2971469486 cites W1990643323 @default.
- W2971469486 cites W2059267945 @default.
- W2971469486 cites W2088290335 @default.
- W2971469486 cites W2438180176 @default.
- W2971469486 cites W2471398485 @default.
- W2971469486 doi "https://doi.org/10.5604/01.3001.0013.4180" @default.
- W2971469486 hasPublicationYear "2019" @default.
- W2971469486 type Work @default.
- W2971469486 sameAs 2971469486 @default.
- W2971469486 citedByCount "0" @default.
- W2971469486 crossrefType "journal-article" @default.
- W2971469486 hasAuthorship W2971469486A5053633296 @default.
- W2971469486 hasAuthorship W2971469486A5054485607 @default.
- W2971469486 hasConcept C178790620 @default.
- W2971469486 hasConcept C185592680 @default.
- W2971469486 hasConcept C2777346864 @default.
- W2971469486 hasConceptScore W2971469486C178790620 @default.
- W2971469486 hasConceptScore W2971469486C185592680 @default.
- W2971469486 hasConceptScore W2971469486C2777346864 @default.
- W2971469486 hasIssue "3(101)" @default.
- W2971469486 hasLocation W29714694861 @default.
- W2971469486 hasOpenAccess W2971469486 @default.
- W2971469486 hasPrimaryLocation W29714694861 @default.
- W2971469486 hasRelatedWork W1983096085 @default.
- W2971469486 hasRelatedWork W2046854371 @default.
- W2971469486 hasRelatedWork W2088669026 @default.
- W2971469486 hasRelatedWork W2317452413 @default.
- W2971469486 hasRelatedWork W2395780673 @default.
- W2971469486 hasRelatedWork W2604890884 @default.
- W2971469486 hasRelatedWork W2949229842 @default.
- W2971469486 hasRelatedWork W2951455053 @default.
- W2971469486 hasRelatedWork W2952812240 @default.
- W2971469486 hasRelatedWork W2995758399 @default.
- W2971469486 hasVolume "36" @default.
- W2971469486 isParatext "false" @default.
- W2971469486 isRetracted "false" @default.
- W2971469486 magId "2971469486" @default.
- W2971469486 workType "article" @default.