FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2971737097> ?p ?o ?g. }

• W2971737097 endingPage "99" @default.
• W2971737097 startingPage "90" @default.
• W2971737097 abstract "Abstract Aims We aimed to investigate the safety of discontinuing oral anticoagulation (OAC) therapy after apparently successful atrial fibrillation (AF) ablation, using data from the Chinese Atrial Fibrillation Registry study. Methods and results We identified 4512 consecutive patients who underwent successful AF ablation between August 2011 and December 2017. Of them, 3149 discontinued OAC 3 months post-ablation (Off-OAC group) and 1363 continued OAC beyond this period (On-OAC group). Regular follow-up examinations were undertaken to detect AF recurrence, monitor OAC therapy, and measure clinical outcomes. Primary outcomes included thromboembolic and major bleeding (MB) events experienced beyond 3 months after ablation. Low thromboembolic and MB event rates were noted in the on-treatment analysis. The incidence rates for thromboembolism were 0.54 [95% confidence interval (CI) 0.39–0.76] and 0.86 (95% CI 0.56–1.30) per 100 patient-years, and that for MB events were 0.19 (95% CI 0.11–0.34) and 0.35 (95% CI 0.18–0.67) per 100 patient-years, for the Off-OAC and On-OAC groups over mean follow-up periods of 24.2 ± 14.7 and 23.0 ± 13.6 months, respectively. Similar results were observed in the intention-to-treat analysis. Previous history of ischaemic stroke (IS)/transient ischaemic attack (TIA)/systemic embolism (SE) [hazard ratio (HR) 3.40, 95% CI 1.92–6.02; P &lt; 0.01] and diabetes mellitus (HR 2.06, 95% CI 1.20–3.55, P = 0.01) were independently associated with thromboembolic events, while OAC discontinuation (HR 0.71, 95% CI 0.41–1.23, P = 0.21) remained insignificant in multivariable analysis. Conclusions This study suggests that it may be safe to discontinue OAC in post-ablation patients under diligent monitoring, in the absence of AF recurrence, history of IS/TIA/SE, and diabetes mellitus. However, further large-scale randomized trials are required to confirm this. Trial registration Chinese Clinical Trial Registry ChiCTR-OCH-13003729. URL: http://www.chictr.org.cn/showproj.aspx?proj=5831." @default.
• W2971737097 created "2019-09-12" @default.
• W2971737097 creator A5009017466 @default.
• W2971737097 creator A5011723711 @default.
• W2971737097 creator A5015205321 @default.
• W2971737097 creator A5021269875 @default.
• W2971737097 creator A5021924497 @default.
• W2971737097 creator A5022256556 @default.
• W2971737097 creator A5024035781 @default.
• W2971737097 creator A5024809686 @default.
• W2971737097 creator A5029937941 @default.
• W2971737097 creator A5034211397 @default.
• W2971737097 creator A5036881486 @default.
• W2971737097 creator A5038405190 @default.
• W2971737097 creator A5041057155 @default.
• W2971737097 creator A5047308765 @default.
• W2971737097 creator A5073316772 @default.
• W2971737097 creator A5074552054 @default.
• W2971737097 creator A5082477851 @default.
• W2971737097 creator A5083218433 @default.
• W2971737097 creator A5083797099 @default.
• W2971737097 date "2019-09-05" @default.
• W2971737097 modified "2023-10-17" @default.
• W2971737097 title "The safety of discontinuation of oral anticoagulation therapy after apparently successful atrial fibrillation ablation: a report from the Chinese Atrial Fibrillation Registry study" @default.
• W2971737097 cites W1904978529 @default.
• W2971737097 cites W1974103997 @default.
• W2971737097 cites W2006507625 @default.
• W2971737097 cites W2014353486 @default.
• W2971737097 cites W2075511073 @default.
• W2971737097 cites W2126958622 @default.
• W2971737097 cites W2127152697 @default.
• W2971737097 cites W2127985968 @default.
• W2971737097 cites W2131656089 @default.
• W2971737097 cites W2150151818 @default.
• W2971737097 cites W2162586165 @default.
• W2971737097 cites W2165779304 @default.
• W2971737097 cites W2316955739 @default.
• W2971737097 cites W2416828311 @default.
• W2971737097 cites W2509795914 @default.
• W2971737097 cites W2546446487 @default.
• W2971737097 cites W2554182612 @default.
• W2971737097 cites W2774243059 @default.
• W2971737097 cites W2989714602 @default.
• W2971737097 cites W4241261201 @default.
• W2971737097 doi "https://doi.org/10.1093/europace/euz235" @default.
• W2971737097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31909431" @default.
• W2971737097 hasPublicationYear "2019" @default.
• W2971737097 type Work @default.
• W2971737097 sameAs 2971737097 @default.
• W2971737097 citedByCount "35" @default.
• W2971737097 countsByYear W29717370972019 @default.
• W2971737097 countsByYear W29717370972020 @default.
• W2971737097 countsByYear W29717370972021 @default.
• W2971737097 countsByYear W29717370972022 @default.
• W2971737097 countsByYear W29717370972023 @default.
• W2971737097 crossrefType "journal-article" @default.
• W2971737097 hasAuthorship W2971737097A5009017466 @default.
• W2971737097 hasAuthorship W2971737097A5011723711 @default.
• W2971737097 hasAuthorship W2971737097A5015205321 @default.
• W2971737097 hasAuthorship W2971737097A5021269875 @default.
• W2971737097 hasAuthorship W2971737097A5021924497 @default.
• W2971737097 hasAuthorship W2971737097A5022256556 @default.
• W2971737097 hasAuthorship W2971737097A5024035781 @default.
• W2971737097 hasAuthorship W2971737097A5024809686 @default.
• W2971737097 hasAuthorship W2971737097A5029937941 @default.
• W2971737097 hasAuthorship W2971737097A5034211397 @default.
• W2971737097 hasAuthorship W2971737097A5036881486 @default.
• W2971737097 hasAuthorship W2971737097A5038405190 @default.
• W2971737097 hasAuthorship W2971737097A5041057155 @default.
• W2971737097 hasAuthorship W2971737097A5047308765 @default.
• W2971737097 hasAuthorship W2971737097A5073316772 @default.
• W2971737097 hasAuthorship W2971737097A5074552054 @default.
• W2971737097 hasAuthorship W2971737097A5082477851 @default.
• W2971737097 hasAuthorship W2971737097A5083218433 @default.
• W2971737097 hasAuthorship W2971737097A5083797099 @default.
• W2971737097 hasBestOaLocation W29717370971 @default.
• W2971737097 hasConcept C120665830 @default.
• W2971737097 hasConcept C121332964 @default.
• W2971737097 hasConcept C126322002 @default.
• W2971737097 hasConcept C127413603 @default.
• W2971737097 hasConcept C141071460 @default.
• W2971737097 hasConcept C164705383 @default.
• W2971737097 hasConcept C207103383 @default.
• W2971737097 hasConcept C2776131983 @default.
• W2971737097 hasConcept C2777185221 @default.
• W2971737097 hasConcept C2778715236 @default.
• W2971737097 hasConcept C2778902805 @default.
• W2971737097 hasConcept C2779161974 @default.
• W2971737097 hasConcept C2780645631 @default.
• W2971737097 hasConcept C44249647 @default.
• W2971737097 hasConcept C61511704 @default.
• W2971737097 hasConcept C71924100 @default.
• W2971737097 hasConcept C78519656 @default.
• W2971737097 hasConceptScore W2971737097C120665830 @default.
• W2971737097 hasConceptScore W2971737097C121332964 @default.
• W2971737097 hasConceptScore W2971737097C126322002 @default.
• W2971737097 hasConceptScore W2971737097C127413603 @default.
• W2971737097 hasConceptScore W2971737097C141071460 @default.

• next