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- W2971748735 endingPage "3350" @default.
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- W2971748735 abstract "The expanding range of treatment options for rheumatoid arthritis (RA), from conventional synthetic disease-modifying antirheumatic drugs (DMARDs) to biological DMARDs (bDMARDs), biosimilar bDMARDs, and targeted synthetic DMARDs, has improved patient outcomes but increased the complexity of treatment decisions. These updated consensus recommendations from the Hong Kong Society of Rheumatology provide guidance on the management of RA, with a focus on how to integrate newly available DMARDs into clinical practice. The recommendations were developed based on evidence from the literature along with local expert opinion. Early diagnosis of RA and prompt initiation of effective therapy remain crucial and we suggest a treat-to-target approach to guide optimal sequencing of DMARDs in RA patients to achieve tight disease control. Newly available DMARDs are incorporated in the treatment algorithm, resulting in a greater range of second-line treatment options. In the event of treatment failure or intolerance, switching to another DMARD with a similar or different mode of action may be considered. Given the variety of available treatments and the heterogeneity of patients with RA, treatment decisions should be tailored to the individual patient taking into consideration prognostic factors, medical comorbidities, drug safety, cost of treatment, and patient preference." @default.
- W2971748735 created "2019-09-12" @default.
- W2971748735 creator A5017924470 @default.
- W2971748735 creator A5020467161 @default.
- W2971748735 creator A5033947419 @default.
- W2971748735 creator A5039003094 @default.
- W2971748735 creator A5054056662 @default.
- W2971748735 date "2019-09-04" @default.
- W2971748735 modified "2023-10-14" @default.
- W2971748735 title "Management of rheumatoid arthritis: 2019 updated consensus recommendations from the Hong Kong Society of Rheumatology" @default.
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