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- W2971762634 endingPage "1329.e70" @default.
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- W2971762634 abstract "The process of heart induction appears to be highly conserved among vertebrates. The endoderm is important for heart induction in vertebrates. The details of the mechanism remain poorly understood. The localized inhibition of canonical Wnt signaling, which is regulated by endogenous Wnt antagonists, is required for heart induction. The size of the developing heart is regulated by inhibitory signals. The bone morphogenetic protein (BMP), Wnt, fibroblast growth factor (FGF) and Notch signaling pathways are important during early heart development. Different transcription factor profiles, in different regions of the original heart field, direct differentiation of the individual subdomains of the developing heart. Using a defined set of transcription factors, it is now possible to reprogram non-cardiac cells to the myocardial lineage." @default.
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- W2971762634 date "2008-12-01" @default.
- W2971762634 modified "2023-10-14" @default.
- W2971762634 title "Guía de práctica clínica de la Sociedad Europea de Cardiología (ESC) para el diagnóstico y tratamiento de la insuficiencia cardiaca aguda y crónica (2008)" @default.
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