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- W2972008561 abstract "Research on <i>in vitro</i> culture and gene editing of domestic spermatogonial stem cells (SSCs) is of considerable interest but remains a challenging issue in animal science. In recent years, some progress on the isolation, purification, and genetic manipulation of porcine SSCs has been reported. Here, we summarize the characteristics of porcine SSCs as well current advances in their <i>in vitro</i> culture, potential usage, and genetic manipulation. Furthermore, we discuss the current application of gene editing in pig cloning technology. Collectively, this commentary aims to summarize the progress made and obstacles encountered in porcine SSC research to better serve animal husbandry, improve livestock fecundity, and enhance potential clinical use." @default.
- W2972008561 created "2019-09-12" @default.
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- W2972008561 date "2019-01-01" @default.
- W2972008561 modified "2023-10-15" @default.
- W2972008561 title "Progress in<em> in vitro</em> culture and gene editing of porcine spermatogonial stem cells" @default.
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- W2972008561 doi "https://doi.org/10.24272/j.issn.2095-8137.2019.051" @default.
- W2972008561 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6755112" @default.
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