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- W2972067166 abstract "Bisphenol A (BPA) is an endocrine-disrupting chemical that is capable of interfering with the normal function of the endocrine system in the body. Exposure to this chemical from BPA-containing materials and the environment is associated with deleterious health effects, including male reproductive abnormalities. A search of the literature demonstrated that BPA, as a toxicant, directly affects the cellular oxidative stress response machinery. Because of its hormone-like properties, it can also bind with specific receptors in target cells. Therefore, the tissue-specific effects of BPA mostly depend on its endocrine-disrupting capabilities and the expression of those particular receptors in target cells. Although studies have shown the possible mechanisms of BPA action in various cell types, a clear consensus has yet to be established. In this review, we summarize the mechanisms of BPA action in spermatozoa by compiling existing information in the literature." @default.
- W2972067166 created "2019-09-12" @default.
- W2972067166 creator A5034098932 @default.
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- W2972067166 date "2019-09-01" @default.
- W2972067166 modified "2023-10-14" @default.
- W2972067166 title "Understanding the molecular mechanisms of bisphenol A action in spermatozoa" @default.
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- W2972067166 doi "https://doi.org/10.5653/cerm.2019.00276" @default.
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