FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2972251664> ?p ?o ?g. }

• W2972251664 endingPage "1721" @default.
• W2972251664 startingPage "1721" @default.
• W2972251664 abstract "The aim of this review was to carry out primary and secondary analyses of 20 randomised controlled trials (RCTs) comparing carotid endarterectomy (CEA) with carotid artery stenting (CAS). A systematic review and meta-analysis of data from 20 RCTs (126 publications) was carried out. Compared with CEA, the 30 day death/stroke rate was significantly higher after CAS in seven RCTs involving 3467 asymptomatic patients (odds ratio [OR] 1.64, 95% confidence interval [CI] 1.02–2.64) and in 10 RCTs involving 5797 symptomatic patients (OR 1.71, 95% CI 1.38–2.11). Excluding procedural risks, late ipsilateral stroke was about 4% at 9 years for both CEA and CAS, i.e., CAS was durable. Reducing procedural death/stroke after CAS may be achieved through better case selection, e.g., performing CEA in (i) symptomatic patients aged > 70 years; (ii) interventions within 14 days of symptom onset; and (iii) situations where stroke risk after CAS is predicted to be higher (segmental/remote plaques, plaque length > 13 mm, heavy burden of white matter lesions [WMLs], where two or more stents might be needed). New WMLs were significantly more common after CAS (52% vs. 17%) and were associated with higher rates of late stroke/transient ischaemic attack (23% vs. 9%), but there was no evidence that new WMLs predisposed towards late cognitive impairment. Restenoses were more common after CAS (10%) but did not increase late ipsilateral stroke. Restenoses (70%–99%) after CEA were associated with a small but significant increase in late ipsilateral stroke (OR 3.87, 95% CI 1.96–7.67; p < .001). CAS confers higher rates of 30 day death/stroke than CEA. After 30 days, ipsilateral stroke is virtually identical for CEA and CAS. Key issues to be resolved include the following: (i) Will newer stent technologies and improved cerebral protection allow CAS to be performed < 14 days after symptom onset with risks similar to CEA? (ii) What is the optimal volume of CAS procedures to maintain competency? (iii) How to deliver better risk factor control and best medical treatment? (iv) Is there a role for CEA/CAS in preventing/reversing cognitive impairment?" @default.
• W2972251664 created "2019-09-12" @default.
• W2972251664 creator A5025585452 @default.
• W2972251664 creator A5078184635 @default.
• W2972251664 creator A5091131617 @default.
• W2972251664 date "2019-11-01" @default.
• W2972251664 modified "2023-09-25" @default.
• W2972251664 title "Overview of Primary and Secondary Analyses From 20 Randomised Controlled Trials Comparing Carotid Artery Stenting With Carotid Endarterectomy" @default.
• W2972251664 cites W1020414206 @default.
• W2972251664 cites W138858833 @default.
• W2972251664 cites W154941835 @default.
• W2972251664 cites W1554749306 @default.
• W2972251664 cites W1557604963 @default.
• W2972251664 cites W1568992978 @default.
• W2972251664 cites W1605370691 @default.
• W2972251664 cites W1802680133 @default.
• W2972251664 cites W1841059984 @default.
• W2972251664 cites W1948938848 @default.
• W2972251664 cites W1955664145 @default.
• W2972251664 cites W1963713297 @default.
• W2972251664 cites W1965652425 @default.
• W2972251664 cites W1965785550 @default.
• W2972251664 cites W1969542240 @default.
• W2972251664 cites W1973436705 @default.
• W2972251664 cites W1973730575 @default.
• W2972251664 cites W1976917595 @default.
• W2972251664 cites W1979303933 @default.
• W2972251664 cites W1979602749 @default.
• W2972251664 cites W1986215651 @default.
• W2972251664 cites W1989579780 @default.
• W2972251664 cites W1998066022 @default.
• W2972251664 cites W1999427229 @default.
• W2972251664 cites W2010264089 @default.
• W2972251664 cites W2016620185 @default.
• W2972251664 cites W2022948683 @default.
• W2972251664 cites W2026357747 @default.
• W2972251664 cites W2029088929 @default.
• W2972251664 cites W2031137081 @default.
• W2972251664 cites W2031277082 @default.
• W2972251664 cites W2032407502 @default.
• W2972251664 cites W2033815773 @default.
• W2972251664 cites W2037985823 @default.
• W2972251664 cites W2038169486 @default.
• W2972251664 cites W2040008271 @default.
• W2972251664 cites W2041012295 @default.
• W2972251664 cites W2041685243 @default.
• W2972251664 cites W2043537980 @default.
• W2972251664 cites W2046776216 @default.
• W2972251664 cites W2059474805 @default.
• W2972251664 cites W2061869426 @default.
• W2972251664 cites W2066684995 @default.
• W2972251664 cites W2073225205 @default.
• W2972251664 cites W2075394347 @default.
• W2972251664 cites W2081059945 @default.
• W2972251664 cites W2084260752 @default.
• W2972251664 cites W2084618484 @default.
• W2972251664 cites W2090693810 @default.
• W2972251664 cites W2094030464 @default.
• W2972251664 cites W2095454015 @default.
• W2972251664 cites W2095625098 @default.
• W2972251664 cites W2097349400 @default.
• W2972251664 cites W2097554249 @default.
• W2972251664 cites W2097894140 @default.
• W2972251664 cites W2100194095 @default.
• W2972251664 cites W2101101366 @default.
• W2972251664 cites W2102827329 @default.
• W2972251664 cites W2107640974 @default.
• W2972251664 cites W2107715463 @default.
• W2972251664 cites W2108075493 @default.
• W2972251664 cites W2109313349 @default.
• W2972251664 cites W2109652445 @default.
• W2972251664 cites W2110288150 @default.
• W2972251664 cites W2118383837 @default.
• W2972251664 cites W2122528416 @default.
• W2972251664 cites W2122743334 @default.
• W2972251664 cites W2124820341 @default.
• W2972251664 cites W2126636620 @default.
• W2972251664 cites W2126710878 @default.
• W2972251664 cites W2127089415 @default.
• W2972251664 cites W2129853770 @default.
• W2972251664 cites W2134476496 @default.
• W2972251664 cites W2135353076 @default.
• W2972251664 cites W2137563759 @default.
• W2972251664 cites W2138614868 @default.
• W2972251664 cites W2140862373 @default.
• W2972251664 cites W2146237298 @default.
• W2972251664 cites W2152662337 @default.
• W2972251664 cites W2153613626 @default.
• W2972251664 cites W2154447272 @default.
• W2972251664 cites W2155465705 @default.
• W2972251664 cites W2157289247 @default.
• W2972251664 cites W2158204470 @default.
• W2972251664 cites W2161274198 @default.
• W2972251664 cites W2164238556 @default.
• W2972251664 cites W2167544064 @default.
• W2972251664 cites W2171424467 @default.
• W2972251664 cites W2171787870 @default.
• W2972251664 cites W2172175117 @default.

• next