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- W2972330596 abstract "The aim of this study was to determine a compatible method for co-production of fucoxanthin and eicosapentaenoic acid of diatom Nitzschia laevis by mixotrophic and heterotrophic cultivation modes in view of cell growth, targeting products’ contents, photosynthesis-related characteristics and carbon partitioning. The results showed that mixotrophic mode enhanced fucoxanthin and eicosapentaenoic acid yields by increasing their precursors of pyruvate and acetyl-CoA at the expense of starch. The increase of chlorophylls and glyceraldehyde 3-phosphate indicated the development of Calvin cycle and carbon repartitioning in mixotrophic mode. Consequently, microalgal cells in mixotrophic mode achieved much higher fucoxanthin (60.12%) and eicosapentaenoic acid (50.67%) contents, and lower starch content (30.2%) compared with heterotrophic mode. Furthermore, fucoxanthin content was positively correlated with eicosapentaenoic acid content (adjusted R2 = 0.96). Taken together, these results showed that the mixotrophic mode could be a promising approach for the co-production of fucoxanthin and eicosapentaenoic acid by Nitzschia laevis." @default.
- W2972330596 created "2019-09-19" @default.
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- W2972330596 date "2019-12-01" @default.
- W2972330596 modified "2023-10-17" @default.
- W2972330596 title "Novel insights into mixotrophic cultivation of Nitzschia laevis for co-production of fucoxanthin and eicosapentaenoic acid" @default.
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- W2972330596 doi "https://doi.org/10.1016/j.biortech.2019.122145" @default.
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