Matches in SemOpenAlex for { <https://semopenalex.org/work/W2972509570> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2972509570 abstract "Abstract. Malini DM, Abadi SA, Madihah, Hermawan W. 2019. The effect of ethanol extract of fruit peel jengkol (Archidendron pauciflorum) to spleen histological structure of streptozotocin-induced diabetic rats (Rattus norvegicus). Nusantara Bioscience 11: 157-161. Diabetes Mellitus (DM) is a chronic endocrine disorder associated with several secondary complications. The spleen is a lymph organ with the main function of filtering red blood cells, immune response and playing any kind of role in diabetes. Despite the currently available anti-diabetic drugs, there are need remedies for alternatives which are economical and safe. One alternative medicine well known by local Indonesian communities to treat DM is the fruit peel of Archidendron pauciflorum. This study aimed to evaluate the histological changes in the spleen following administration of ethanol extract of fruit peel Archidendron Pauciflorum (EEJFP) in the streptozotocin (STZ) - induced diabetic rats. Diabetic rats were used in this study consisting of six groups of four animals each. The treatments given are NC (CMC solution 0.5%), Positive Control (CMC solution 0.5%), G (glibenclamide), Treatment 1, 2, and 3 (EEJFP dose 385; 770; 1540 mg/kg bw). All of the treatment was administered orally to the experimental rats 14 days following induction. The spleen was collected and the histological study was performed using hematoxylin and eosin (H&E). The parameters observed were the number of necrosis and cell damage score, including fat degeneration, hydropic degeneration, and inflammatory cell. The result showed that EEJFP at dose 385 mg/kg bw and 770 mg/kg bw gave significant recovery (p<0.05) on spleen damage by the decreased of the number of necrotic cells and cell damage score which lower than other treatments and compared to negative control group. It was concluded that doses of 385 mg/kg bw EEJFP are the optimum dose to improve the histological structure of spleen damage in diabetic rats." @default.
- W2972509570 created "2019-09-19" @default.
- W2972509570 creator A5024382326 @default.
- W2972509570 creator A5033703513 @default.
- W2972509570 creator A5068250339 @default.
- W2972509570 creator A5084902359 @default.
- W2972509570 date "2019-09-12" @default.
- W2972509570 modified "2023-09-24" @default.
- W2972509570 title "The effect of ethanol extract of fruit peel jengkol (Archidendron pauciflorum) to spleen histological structure of streptozotocin-induced diabetic rats (Rattus norvegicus)" @default.
- W2972509570 cites W2053025683 @default.
- W2972509570 cites W2117353450 @default.
- W2972509570 cites W2119304571 @default.
- W2972509570 cites W2137706047 @default.
- W2972509570 cites W2140602121 @default.
- W2972509570 cites W2141107080 @default.
- W2972509570 cites W2147344086 @default.
- W2972509570 cites W2181837267 @default.
- W2972509570 cites W2740358460 @default.
- W2972509570 doi "https://doi.org/10.13057/nusbiosci/n110208" @default.
- W2972509570 hasPublicationYear "2019" @default.
- W2972509570 type Work @default.
- W2972509570 sameAs 2972509570 @default.
- W2972509570 citedByCount "0" @default.
- W2972509570 crossrefType "journal-article" @default.
- W2972509570 hasAuthorship W2972509570A5024382326 @default.
- W2972509570 hasAuthorship W2972509570A5033703513 @default.
- W2972509570 hasAuthorship W2972509570A5068250339 @default.
- W2972509570 hasAuthorship W2972509570A5084902359 @default.
- W2972509570 hasBestOaLocation W29725095701 @default.
- W2972509570 hasConcept C125473707 @default.
- W2972509570 hasConcept C126322002 @default.
- W2972509570 hasConcept C134018914 @default.
- W2972509570 hasConcept C185592680 @default.
- W2972509570 hasConcept C203014093 @default.
- W2972509570 hasConcept C204232928 @default.
- W2972509570 hasConcept C2779280383 @default.
- W2972509570 hasConcept C2779768347 @default.
- W2972509570 hasConcept C2780161600 @default.
- W2972509570 hasConcept C2780931953 @default.
- W2972509570 hasConcept C2781005915 @default.
- W2972509570 hasConcept C503630168 @default.
- W2972509570 hasConcept C55493867 @default.
- W2972509570 hasConcept C555293320 @default.
- W2972509570 hasConcept C556039675 @default.
- W2972509570 hasConcept C71924100 @default.
- W2972509570 hasConcept C8891405 @default.
- W2972509570 hasConcept C98274493 @default.
- W2972509570 hasConceptScore W2972509570C125473707 @default.
- W2972509570 hasConceptScore W2972509570C126322002 @default.
- W2972509570 hasConceptScore W2972509570C134018914 @default.
- W2972509570 hasConceptScore W2972509570C185592680 @default.
- W2972509570 hasConceptScore W2972509570C203014093 @default.
- W2972509570 hasConceptScore W2972509570C204232928 @default.
- W2972509570 hasConceptScore W2972509570C2779280383 @default.
- W2972509570 hasConceptScore W2972509570C2779768347 @default.
- W2972509570 hasConceptScore W2972509570C2780161600 @default.
- W2972509570 hasConceptScore W2972509570C2780931953 @default.
- W2972509570 hasConceptScore W2972509570C2781005915 @default.
- W2972509570 hasConceptScore W2972509570C503630168 @default.
- W2972509570 hasConceptScore W2972509570C55493867 @default.
- W2972509570 hasConceptScore W2972509570C555293320 @default.
- W2972509570 hasConceptScore W2972509570C556039675 @default.
- W2972509570 hasConceptScore W2972509570C71924100 @default.
- W2972509570 hasConceptScore W2972509570C8891405 @default.
- W2972509570 hasConceptScore W2972509570C98274493 @default.
- W2972509570 hasLocation W29725095701 @default.
- W2972509570 hasOpenAccess W2972509570 @default.
- W2972509570 hasPrimaryLocation W29725095701 @default.
- W2972509570 hasRelatedWork W1514071890 @default.
- W2972509570 hasRelatedWork W2087802449 @default.
- W2972509570 hasRelatedWork W2100896956 @default.
- W2972509570 hasRelatedWork W2117831463 @default.
- W2972509570 hasRelatedWork W2119047107 @default.
- W2972509570 hasRelatedWork W2124310814 @default.
- W2972509570 hasRelatedWork W2324295651 @default.
- W2972509570 hasRelatedWork W2548635472 @default.
- W2972509570 hasRelatedWork W2551830442 @default.
- W2972509570 hasRelatedWork W2594390817 @default.
- W2972509570 hasRelatedWork W2794541102 @default.
- W2972509570 hasRelatedWork W2810142273 @default.
- W2972509570 hasRelatedWork W2892964350 @default.
- W2972509570 hasRelatedWork W2914395948 @default.
- W2972509570 hasRelatedWork W2921553681 @default.
- W2972509570 hasRelatedWork W2953040549 @default.
- W2972509570 hasRelatedWork W2989138800 @default.
- W2972509570 hasRelatedWork W2993255481 @default.
- W2972509570 hasRelatedWork W3043690880 @default.
- W2972509570 hasRelatedWork W3212081408 @default.
- W2972509570 isParatext "false" @default.
- W2972509570 isRetracted "false" @default.
- W2972509570 magId "2972509570" @default.
- W2972509570 workType "article" @default.