FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2972633883> ?p ?o ?g. }

• W2972633883 endingPage "E59" @default.
• W2972633883 startingPage "E59" @default.
• W2972633883 abstract "Breast cancer-related lymphedema can significantly compromise physical and psychosocial quality of life. Bioimpedance spectroscopy (BIS) is an established tool for measuring extracellular fluid in lymphedema. The purpose of this study was to determine the incidence of BIS-detected lymphedema using the L-Dex® and identify risk factors associated with a positive L-Dex® score. We performed a retrospective review of our institutional database to identify patients who underwent L-Dex® U400 measurements from 2014 to 2018. Patients receiving treatment for an ipsilateral recurrence or with a history of a contralateral breast cancer were excluded. Patients with a score of >10 L-Dex® units or with an increase of >10 units from baseline were considered to have a positive score. Clinical lymphedema was determined by documentation in the chart at the time of positive L-Dex® measurement. Otherwise, patients were considered to have subclinical lymphedema. All therapies received with at least 30 days of follow-up at the time of most recent measurement were recorded. Patient, disease, and treatment related factors were collected and compared using the Chi-squared and Fisher’s exact tests. Fifty-three patients met the study criteria. Median age was 51 (range, 30-84), and median follow-up from surgery to most recent L-Dex® measurement was 215 days (range, 43-2,938). Thirty patients (56.6%) underwent mastectomy, and 22 (41.5%) underwent axillary lymph node dissection (ALND). Median number of LNs removed with ALND was 10 and with sentinel node biopsy (SLNB) was 2. Thirty-three patients (62.3%) received whole breast radiation, with 23 (43.4%) receiving treatment to the regional LNs. Twelve patients (22.6%) had a positive L-Dex® score, 8 from the ALND subset (36.4%) and 4 from the SLNB subset (12.9%). There were no significant differences in age, race, tumor laterality, breast surgery, T stage, N stage, receipt of chemotherapy, or RT fields (none, breast only, and breast with regional LNs; p=0.16) in patients with a positive L-Dex® score. ALND was significantly more common (66.7% vs. 34.2%, p=0.04). BMI>30 approached significance (58.3% vs. 29.3%, p=0.06). Subclinical lymphedema was noted in 7 of the 12 patients (58.3%). No significant differences were identified comparing patients with subclinical lymphedema to those with negative scores. Among the 5 patients with clinical lymphedema, all were included in the subset of patients undergoing ALND and receiving regional nodal RT (n=18). No patients who received any other combination of axillary surgery and RT developed clinical lymphedema, (p=0.009 and p=0.039, respectively). Mean number of LNs removed in patients with clinical lymphedema was 14.2 (SD=5.6). The combination of ALND and regional nodal RT is strongly associated with the development of clinical lymphedema, with an incidence rate of 27.8% in this study. It is difficult to identify patients at risk for subclinical BIS-detected lymphedema." @default.
• W2972633883 created "2019-09-19" @default.
• W2972633883 creator A5009395077 @default.
• W2972633883 creator A5012650103 @default.
• W2972633883 creator A5046167207 @default.
• W2972633883 creator A5057983228 @default.
• W2972633883 creator A5063899863 @default.
• W2972633883 date "2019-09-01" @default.
• W2972633883 modified "2023-09-27" @default.
• W2972633883 title "Risk Factors for the Development of Clinical and Subclinical Lymphedema Detected by Bioimpedance Spectroscopy" @default.
• W2972633883 doi "https://doi.org/10.1016/j.ijrobp.2019.06.2396" @default.
• W2972633883 hasPublicationYear "2019" @default.
• W2972633883 type Work @default.
• W2972633883 sameAs 2972633883 @default.
• W2972633883 citedByCount "0" @default.
• W2972633883 crossrefType "journal-article" @default.
• W2972633883 hasAuthorship W2972633883A5009395077 @default.
• W2972633883 hasAuthorship W2972633883A5012650103 @default.
• W2972633883 hasAuthorship W2972633883A5046167207 @default.
• W2972633883 hasAuthorship W2972633883A5057983228 @default.
• W2972633883 hasAuthorship W2972633883A5063899863 @default.
• W2972633883 hasBestOaLocation W29726338831 @default.
• W2972633883 hasConcept C113280763 @default.
• W2972633883 hasConcept C121608353 @default.
• W2972633883 hasConcept C126322002 @default.
• W2972633883 hasConcept C141071460 @default.
• W2972633883 hasConcept C2776608951 @default.
• W2972633883 hasConcept C2777757722 @default.
• W2972633883 hasConcept C2780212769 @default.
• W2972633883 hasConcept C2780849966 @default.
• W2972633883 hasConcept C2781392513 @default.
• W2972633883 hasConcept C530470458 @default.
• W2972633883 hasConcept C71924100 @default.
• W2972633883 hasConceptScore W2972633883C113280763 @default.
• W2972633883 hasConceptScore W2972633883C121608353 @default.
• W2972633883 hasConceptScore W2972633883C126322002 @default.
• W2972633883 hasConceptScore W2972633883C141071460 @default.
• W2972633883 hasConceptScore W2972633883C2776608951 @default.
• W2972633883 hasConceptScore W2972633883C2777757722 @default.
• W2972633883 hasConceptScore W2972633883C2780212769 @default.
• W2972633883 hasConceptScore W2972633883C2780849966 @default.
• W2972633883 hasConceptScore W2972633883C2781392513 @default.
• W2972633883 hasConceptScore W2972633883C530470458 @default.
• W2972633883 hasConceptScore W2972633883C71924100 @default.
• W2972633883 hasIssue "1" @default.
• W2972633883 hasLocation W29726338831 @default.
• W2972633883 hasOpenAccess W2972633883 @default.
• W2972633883 hasPrimaryLocation W29726338831 @default.
• W2972633883 hasRelatedWork W1976264124 @default.
• W2972633883 hasRelatedWork W1996530877 @default.
• W2972633883 hasRelatedWork W2033807945 @default.
• W2972633883 hasRelatedWork W2156920679 @default.
• W2972633883 hasRelatedWork W2391886816 @default.
• W2972633883 hasRelatedWork W2765902468 @default.
• W2972633883 hasRelatedWork W2944285162 @default.
• W2972633883 hasRelatedWork W3003452953 @default.
• W2972633883 hasRelatedWork W4353015004 @default.
• W2972633883 hasRelatedWork W68729977 @default.
• W2972633883 hasVolume "105" @default.
• W2972633883 isParatext "false" @default.
• W2972633883 isRetracted "false" @default.
• W2972633883 magId "2972633883" @default.
• W2972633883 workType "article" @default.