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- W2973006268 abstract "As a physiologic process, reflux commonly occurred following a daily meal with no sign. Heartburn in Traditional Persian Medicine (TPM) has been defined as “Harghat-e-me’adeh” or “Josha-e-hāmez”. Regarding the clinical importance of this complication, in current work a related traditional formulation containing True cardamom, Ginger, Black cumin and Mastic, selected from various related traditional formulations which have been extracted from three main Qarabadin textbooks of Persian medicine. Following content authentication and microscopic characterization, various tablet formulations were prepared using excipients. The final formulation was a tablet containing those ingredients in 28% for each, with avicel (9/8%) and Magnesium stearate (0.2%) as a binder, respectively. Chemical composition analysis was carried out using Gas Chromatography/ Mass spectrometry apparatus (GC/MS). α-terpinyl acetate (34.02%), 1,8- cineole (18.07), cumin-aldehyde (8.15), and γ-terpinene (11.74%) were identified as major constituents. The content determination of the tablet was performed via Gas Chromatography/ Flame ionization detector (GC/FID). The fingerprint obtained from IR Spectroscopy. Data on pharmaceutical assessment were included friability (less than 1%), weight variation (less than 1%), hardness (6.5±0.5 kg/cm2), disintegration time (less than 35 min) and thickness (3.02±.04 mm). The yield of essential oil extracted from the tablet was found 3%, and each tablet contained 1.33 mg γ-terpinene. This finished product can be introduced as medicine for clinical trial and pharmaceutical industry." @default.
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- W2973006268 date "2019-06-01" @default.
- W2973006268 modified "2023-09-26" @default.
- W2973006268 title "A Gas Chromatographic-Based Method for Determination of γ- terpinene in a herbal solid dosage form" @default.
- W2973006268 doi "https://doi.org/10.30476/tips.2019.83049.1021" @default.
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