FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2973133052> ?p ?o ?g. }

• W2973133052 endingPage "e02411" @default.
• W2973133052 startingPage "e02411" @default.
• W2973133052 abstract "To our knowledge, HIV transmitted drug resistance (TDR) patterns have not been characterized specifically in Santa Clara County (SCC), California, one of the largest counties by population in the United States. Understanding TDR here will help improve antiretroviral therapy outcomes and prevent future transmission events.This is a retrospective analysis of TDR among patients establishing care at a county HIV clinic at the Santa Clara Valley Health and Hospital System. We identified 206 treatment-naive individuals who were newly diagnosed with HIV between 2006-2013. Using these individuals, we assessed the prevalence and temporal trends of total TDR and TDR to nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), and integrase strand transfer inhibitors (INSTIs).We identified a total TDR prevalence of 17.5% during 2006-2013 (7.3% NNRTI, 6.8% NRTI, 2.4% PI, 2.9% INSTI) with 1.9% exhibiting dual-class resistance. Total TDR prevalence initially ranged between 19.0-22.7% during 2006-2008 and decreased to within 10.5-16.2% during 2011-2013, though this decrease was not significant (p = 0.42). NRTI TDR decreased from 22.7% in 2006 to 5.3% in 2013 (p = 0.02), and NNRTI TDR appeared to fluctuate between 2.7-13.5% (p = 0.96). PI and INSTI TDR remained low, with noted E138A prevalence of 2.9%.The prevalence of TDR was substantial among newly diagnosed, treatment-naive individuals establishing care at a SCC-based county HIV clinic from 2006 to 2013. This, along with the presence of transmitted mutations associated with INSTI resistance, warrants continued surveillance of TDR in SCC and use of baseline genotyping prior to antiretroviral therapy initiation." @default.
• W2973133052 created "2019-09-19" @default.
• W2973133052 creator A5036374472 @default.
• W2973133052 creator A5051452114 @default.
• W2973133052 date "2019-09-01" @default.
• W2973133052 modified "2023-09-26" @default.
• W2973133052 title "Surveillance of transmitted HIV drug resistance among newly diagnosed, treatment-naive individuals at a county HIV clinic in Santa Clara County" @default.
• W2973133052 cites W1965509687 @default.
• W2973133052 cites W1966063036 @default.
• W2973133052 cites W1989820477 @default.
• W2973133052 cites W2022893525 @default.
• W2973133052 cites W2025593741 @default.
• W2973133052 cites W2032847961 @default.
• W2973133052 cites W2038084391 @default.
• W2973133052 cites W2045092579 @default.
• W2973133052 cites W2054469024 @default.
• W2973133052 cites W2069388608 @default.
• W2973133052 cites W2075039947 @default.
• W2973133052 cites W2109046728 @default.
• W2973133052 cites W2115919618 @default.
• W2973133052 cites W2122999152 @default.
• W2973133052 cites W2147547300 @default.
• W2973133052 cites W2151238491 @default.
• W2973133052 cites W2152830821 @default.
• W2973133052 cites W2152880150 @default.
• W2973133052 cites W2154164013 @default.
• W2973133052 cites W2170237371 @default.
• W2973133052 cites W2464028366 @default.
• W2973133052 cites W2523305619 @default.
• W2973133052 cites W2597948702 @default.
• W2973133052 cites W2746562707 @default.
• W2973133052 cites W2756209168 @default.
• W2973133052 cites W2771061022 @default.
• W2973133052 cites W2804409418 @default.
• W2973133052 cites W2884912891 @default.
• W2973133052 cites W2909647557 @default.
• W2973133052 cites W2921974399 @default.
• W2973133052 cites W2924309353 @default.
• W2973133052 cites W2989941609 @default.
• W2973133052 doi "https://doi.org/10.1016/j.heliyon.2019.e02411" @default.
• W2973133052 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6744593" @default.
• W2973133052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31535044" @default.
• W2973133052 hasPublicationYear "2019" @default.
• W2973133052 type Work @default.
• W2973133052 sameAs 2973133052 @default.
• W2973133052 citedByCount "3" @default.
• W2973133052 countsByYear W29731330522021 @default.
• W2973133052 countsByYear W29731330522023 @default.
• W2973133052 crossrefType "journal-article" @default.
• W2973133052 hasAuthorship W2973133052A5036374472 @default.
• W2973133052 hasAuthorship W2973133052A5051452114 @default.
• W2973133052 hasBestOaLocation W29731330521 @default.
• W2973133052 hasConcept C114851261 @default.
• W2973133052 hasConcept C119599485 @default.
• W2973133052 hasConcept C126322002 @default.
• W2973133052 hasConcept C127413603 @default.
• W2973133052 hasConcept C142462285 @default.
• W2973133052 hasConcept C14430832 @default.
• W2973133052 hasConcept C159047783 @default.
• W2973133052 hasConcept C2777302000 @default.
• W2973133052 hasConcept C2778451633 @default.
• W2973133052 hasConcept C2908647359 @default.
• W2973133052 hasConcept C2993143319 @default.
• W2973133052 hasConcept C3013748606 @default.
• W2973133052 hasConcept C71924100 @default.
• W2973133052 hasConcept C761482 @default.
• W2973133052 hasConcept C86803240 @default.
• W2973133052 hasConcept C89423630 @default.
• W2973133052 hasConcept C99454951 @default.
• W2973133052 hasConceptScore W2973133052C114851261 @default.
• W2973133052 hasConceptScore W2973133052C119599485 @default.
• W2973133052 hasConceptScore W2973133052C126322002 @default.
• W2973133052 hasConceptScore W2973133052C127413603 @default.
• W2973133052 hasConceptScore W2973133052C142462285 @default.
• W2973133052 hasConceptScore W2973133052C14430832 @default.
• W2973133052 hasConceptScore W2973133052C159047783 @default.
• W2973133052 hasConceptScore W2973133052C2777302000 @default.
• W2973133052 hasConceptScore W2973133052C2778451633 @default.
• W2973133052 hasConceptScore W2973133052C2908647359 @default.
• W2973133052 hasConceptScore W2973133052C2993143319 @default.
• W2973133052 hasConceptScore W2973133052C3013748606 @default.
• W2973133052 hasConceptScore W2973133052C71924100 @default.
• W2973133052 hasConceptScore W2973133052C761482 @default.
• W2973133052 hasConceptScore W2973133052C86803240 @default.
• W2973133052 hasConceptScore W2973133052C89423630 @default.
• W2973133052 hasConceptScore W2973133052C99454951 @default.
• W2973133052 hasIssue "9" @default.
• W2973133052 hasLocation W29731330521 @default.
• W2973133052 hasLocation W29731330522 @default.
• W2973133052 hasLocation W29731330523 @default.
• W2973133052 hasLocation W29731330524 @default.
• W2973133052 hasLocation W29731330525 @default.
• W2973133052 hasOpenAccess W2973133052 @default.
• W2973133052 hasPrimaryLocation W29731330521 @default.
• W2973133052 hasRelatedWork W2110471430 @default.
• W2973133052 hasRelatedWork W2136637937 @default.
• W2973133052 hasRelatedWork W2395767748 @default.
• W2973133052 hasRelatedWork W2462079933 @default.

• next