FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2973162584> ?p ?o ?g. }

• W2973162584 abstract "Arthur de Carvalho Drops® (ACD) is a traditional Brazilian herbal medicine used to treat functional gastrointestinal disorders (FGIDs). ACD is a formulation of herbal extracts from Matricaria recutita (chamomile), Foeniculum vulgare (fennel) and Gentiana lutea L. (gentian). Considering the popular use for FGIDs, the aim of this work was to investigate the ACD effect on gastric and intestinal parameters with emphasis in a mechanistic approach using isolated duodenal preparations of rodents. Analytical method was developed and validated for quantify three actives principles/markers (Apigenin-7-glucoside, gentiopicroside and anethole) in ACD. The treatment with ACD significantly reduced the emetogenic stimuli induced by cisplatin in rats, showed a laxative effect, reduced the bethanechol-enhanced gastrointestinal transit and completely reversed the contraction induced by carbachol in rat duodenum. However, ACD did not alter the secretory gastric volume or total gastric acidity. The ACD affect the contractions of duodenal smooth muscle mediated by Ca2+ channels and it is also able to inhibit the contractile response mediated by the release from its intracellular store. Furthermore, the relaxant effects of ACD appear independent of the nitric oxide pathway in rat duodenum. These results suggest that ACD could be beneficial for the treatment of disorders of the gastrointestinal tract." @default.
• W2973162584 created "2019-09-19" @default.
• W2973162584 creator A5009830810 @default.
• W2973162584 creator A5010490266 @default.
• W2973162584 creator A5018190141 @default.
• W2973162584 creator A5018593869 @default.
• W2973162584 creator A5021062494 @default.
• W2973162584 creator A5028429772 @default.
• W2973162584 creator A5039343184 @default.
• W2973162584 creator A5052388336 @default.
• W2973162584 creator A5065679072 @default.
• W2973162584 date "2019-09-01" @default.
• W2973162584 modified "2023-09-27" @default.
• W2973162584 title "Gastrointestinal effects of standardized Brazilian phytomedicine (Arthur de Carvalho Drops®) containing Matricaria recutita, Gentiana lutea and Foeniculum vulgare" @default.
• W2973162584 cites W101391877 @default.
• W2973162584 cites W1853697687 @default.
• W2973162584 cites W185571754 @default.
• W2973162584 cites W1966133025 @default.
• W2973162584 cites W1976212641 @default.
• W2973162584 cites W2000271138 @default.
• W2973162584 cites W2003524178 @default.
• W2973162584 cites W2011574134 @default.
• W2973162584 cites W2028278455 @default.
• W2973162584 cites W2028385335 @default.
• W2973162584 cites W2028483480 @default.
• W2973162584 cites W2030118078 @default.
• W2973162584 cites W2033089640 @default.
• W2973162584 cites W2033206396 @default.
• W2973162584 cites W2034510247 @default.
• W2973162584 cites W2038050539 @default.
• W2973162584 cites W2038462428 @default.
• W2973162584 cites W2038574658 @default.
• W2973162584 cites W2042493641 @default.
• W2973162584 cites W2052586356 @default.
• W2973162584 cites W2052647898 @default.
• W2973162584 cites W2057938244 @default.
• W2973162584 cites W2064236179 @default.
• W2973162584 cites W2067120159 @default.
• W2973162584 cites W2070989492 @default.
• W2973162584 cites W2072491112 @default.
• W2973162584 cites W2074457753 @default.
• W2973162584 cites W2076279918 @default.
• W2973162584 cites W2088723911 @default.
• W2973162584 cites W2089742414 @default.
• W2973162584 cites W2106546953 @default.
• W2973162584 cites W2117312810 @default.
• W2973162584 cites W2119497316 @default.
• W2973162584 cites W2144190078 @default.
• W2973162584 cites W2144779736 @default.
• W2973162584 cites W2160942950 @default.
• W2973162584 cites W2165231575 @default.
• W2973162584 cites W2165793347 @default.
• W2973162584 cites W2182511308 @default.
• W2973162584 cites W2284362120 @default.
• W2973162584 cites W2326429678 @default.
• W2973162584 cites W2337312736 @default.
• W2973162584 cites W2344997643 @default.
• W2973162584 cites W2396040288 @default.
• W2973162584 cites W2424645866 @default.
• W2973162584 cites W2510603230 @default.
• W2973162584 cites W2771882445 @default.
• W2973162584 cites W3200213521 @default.
• W2973162584 cites W577877513 @default.
• W2973162584 cites W58488370 @default.
• W2973162584 doi "https://doi.org/10.1016/j.pathophys.2019.09.002" @default.
• W2973162584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31668916" @default.
• W2973162584 hasPublicationYear "2019" @default.
• W2973162584 type Work @default.
• W2973162584 sameAs 2973162584 @default.
• W2973162584 citedByCount "5" @default.
• W2973162584 countsByYear W29731625842020 @default.
• W2973162584 countsByYear W29731625842021 @default.
• W2973162584 countsByYear W29731625842022 @default.
• W2973162584 countsByYear W29731625842023 @default.
• W2973162584 crossrefType "journal-article" @default.
• W2973162584 hasAuthorship W2973162584A5009830810 @default.
• W2973162584 hasAuthorship W2973162584A5010490266 @default.
• W2973162584 hasAuthorship W2973162584A5018190141 @default.
• W2973162584 hasAuthorship W2973162584A5018593869 @default.
• W2973162584 hasAuthorship W2973162584A5021062494 @default.
• W2973162584 hasAuthorship W2973162584A5028429772 @default.
• W2973162584 hasAuthorship W2973162584A5039343184 @default.
• W2973162584 hasAuthorship W2973162584A5052388336 @default.
• W2973162584 hasAuthorship W2973162584A5065679072 @default.
• W2973162584 hasConcept C142724271 @default.
• W2973162584 hasConcept C204787440 @default.
• W2973162584 hasConcept C2778993495 @default.
• W2973162584 hasConcept C2780010996 @default.
• W2973162584 hasConcept C556039675 @default.
• W2973162584 hasConcept C71924100 @default.
• W2973162584 hasConcept C98274493 @default.
• W2973162584 hasConceptScore W2973162584C142724271 @default.
• W2973162584 hasConceptScore W2973162584C204787440 @default.
• W2973162584 hasConceptScore W2973162584C2778993495 @default.
• W2973162584 hasConceptScore W2973162584C2780010996 @default.
• W2973162584 hasConceptScore W2973162584C556039675 @default.
• W2973162584 hasConceptScore W2973162584C71924100 @default.
• W2973162584 hasConceptScore W2973162584C98274493 @default.
• W2973162584 hasLocation W29731625841 @default.
• W2973162584 hasLocation W29731625842 @default.

• next