Matches in SemOpenAlex for { <https://semopenalex.org/work/W2973172011> ?p ?o ?g. }
- W2973172011 endingPage "683" @default.
- W2973172011 startingPage "677" @default.
- W2973172011 abstract "Background/Context: Glioblastoma (GB) is the most common primary brain tumour in adults and it is associated with a high mortality rate. According to the stem cell theory, the growth, relapse and treatment response of GB is determined by the stem cell subpopulation present in the tumour.Objective: Our aim is to study the prognostic value of stem cell markers (CD44, Nestin, Olig2 and SOX2) in a series of homogeneously treated GBs.Material and methods: We study 280 GBs treated with STUPP acheme with a histologican review of the cases and TMA with a máximum of 4 spots for each case. Each slide was immunohistochemically stained and Reading. We compared the immunohistochemical results with survival tme.Results: Only SOX2 immunoexpression (IE) excedding 10% of the tumour cells was found to be related to good survival (p= 0.037) in univariate analysis. However, amultivariate analysis indicate the age, surgery and MGMT promotes methylation but no SOX2 IE are prognostic factors.Conclusions: We conclude the immunohistochemical studies of stem cell markers in GB are not useful for predicting prognosis in daily practice." @default.
- W2973172011 created "2019-09-19" @default.
- W2973172011 creator A5004132264 @default.
- W2973172011 creator A5011383516 @default.
- W2973172011 creator A5012178121 @default.
- W2973172011 creator A5012690140 @default.
- W2973172011 creator A5033699618 @default.
- W2973172011 creator A5037165485 @default.
- W2973172011 creator A5046643880 @default.
- W2973172011 creator A5080151764 @default.
- W2973172011 creator A5090444091 @default.
- W2973172011 date "2019-09-08" @default.
- W2973172011 modified "2023-10-18" @default.
- W2973172011 title "Prognostic value of stem cell markers in glioblastoma" @default.
- W2973172011 cites W1150044964 @default.
- W2973172011 cites W1493594926 @default.
- W2973172011 cites W1510898037 @default.
- W2973172011 cites W1960333596 @default.
- W2973172011 cites W1973997928 @default.
- W2973172011 cites W1975422371 @default.
- W2973172011 cites W1980591417 @default.
- W2973172011 cites W1987081782 @default.
- W2973172011 cites W1993638375 @default.
- W2973172011 cites W2001544973 @default.
- W2973172011 cites W2017736079 @default.
- W2973172011 cites W2026541878 @default.
- W2973172011 cites W2037100155 @default.
- W2973172011 cites W2041822919 @default.
- W2973172011 cites W2049530893 @default.
- W2973172011 cites W2053493373 @default.
- W2973172011 cites W2073276804 @default.
- W2973172011 cites W2082724230 @default.
- W2973172011 cites W2096287682 @default.
- W2973172011 cites W2097292001 @default.
- W2973172011 cites W2097656227 @default.
- W2973172011 cites W2102398739 @default.
- W2973172011 cites W2103192556 @default.
- W2973172011 cites W2113942802 @default.
- W2973172011 cites W2124021558 @default.
- W2973172011 cites W2126000912 @default.
- W2973172011 cites W2137103099 @default.
- W2973172011 cites W2145261791 @default.
- W2973172011 cites W2150197150 @default.
- W2973172011 cites W2151425315 @default.
- W2973172011 cites W2156545134 @default.
- W2973172011 cites W2161978587 @default.
- W2973172011 cites W2164012688 @default.
- W2973172011 cites W2170274776 @default.
- W2973172011 cites W2309276911 @default.
- W2973172011 cites W2461189927 @default.
- W2973172011 cites W2564248192 @default.
- W2973172011 cites W2569898767 @default.
- W2973172011 cites W2586928611 @default.
- W2973172011 cites W2757049764 @default.
- W2973172011 doi "https://doi.org/10.1080/1354750x.2019.1652345" @default.
- W2973172011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31496301" @default.
- W2973172011 hasPublicationYear "2019" @default.
- W2973172011 type Work @default.
- W2973172011 sameAs 2973172011 @default.
- W2973172011 citedByCount "5" @default.
- W2973172011 countsByYear W29731720112020 @default.
- W2973172011 countsByYear W29731720112022 @default.
- W2973172011 countsByYear W29731720112023 @default.
- W2973172011 crossrefType "journal-article" @default.
- W2973172011 hasAuthorship W2973172011A5004132264 @default.
- W2973172011 hasAuthorship W2973172011A5011383516 @default.
- W2973172011 hasAuthorship W2973172011A5012178121 @default.
- W2973172011 hasAuthorship W2973172011A5012690140 @default.
- W2973172011 hasAuthorship W2973172011A5033699618 @default.
- W2973172011 hasAuthorship W2973172011A5037165485 @default.
- W2973172011 hasAuthorship W2973172011A5046643880 @default.
- W2973172011 hasAuthorship W2973172011A5080151764 @default.
- W2973172011 hasAuthorship W2973172011A5090444091 @default.
- W2973172011 hasConcept C104317684 @default.
- W2973172011 hasConcept C126322002 @default.
- W2973172011 hasConcept C136302470 @default.
- W2973172011 hasConcept C136834591 @default.
- W2973172011 hasConcept C142724271 @default.
- W2973172011 hasConcept C143998085 @default.
- W2973172011 hasConcept C144301174 @default.
- W2973172011 hasConcept C1491633281 @default.
- W2973172011 hasConcept C151730666 @default.
- W2973172011 hasConcept C204232928 @default.
- W2973172011 hasConcept C2777738006 @default.
- W2973172011 hasConcept C2777933648 @default.
- W2973172011 hasConcept C2779343474 @default.
- W2973172011 hasConcept C2780932548 @default.
- W2973172011 hasConcept C28328180 @default.
- W2973172011 hasConcept C38180746 @default.
- W2973172011 hasConcept C54355233 @default.
- W2973172011 hasConcept C55493867 @default.
- W2973172011 hasConcept C71924100 @default.
- W2973172011 hasConcept C86339819 @default.
- W2973172011 hasConcept C86803240 @default.
- W2973172011 hasConceptScore W2973172011C104317684 @default.
- W2973172011 hasConceptScore W2973172011C126322002 @default.
- W2973172011 hasConceptScore W2973172011C136302470 @default.
- W2973172011 hasConceptScore W2973172011C136834591 @default.