Matches in SemOpenAlex for { <https://semopenalex.org/work/W2973702896> ?p ?o ?g. }
- W2973702896 endingPage "151357" @default.
- W2973702896 startingPage "151357" @default.
- W2973702896 abstract "Understanding the evolutionary path of M. catarrhalis from macrolide-susceptible to macrolide-resistant organism, is important for hindering macrolide resistance from propagation. Multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE) and whole genome SNP typing (WGST), as useful and practical typing tools, have both advantages and disadvantages. We studied the utility of these 3 typing methods, including the level of agreement, consistency and drawbacks, in characterizing M. catarrhalis clones and clonal complexes. We focused on four clonal complexes [CC224, CC363, CC449 (CCN10) and CC446 (CCN08)] and found that PFGE and WGST had a high level of agreement and a proper consistency of the same clone or very closely related clones, while MLST is less discriminatory for different clones. Furthermore, we also established an evolutionary distance cut-off value for “The same clone”. Moreover, we detected macrolide-resistant M. catarrhalis in CC224, which had previously been considered as a macrolide-susceptible clonal complex. A higher number of isolates belonged to ST215 compared to ST446, implying that ST215 is more likely to be the primary founder. Our study also demonstrated that all the four clonal complexes belong to the M. catarrhalis lineage 1, which is considered to be related to increased virulence potential and serum resistance. We also observed that copB II was highly related to CC449 and LOS type B was mainly confined in CC224. In conclusion, these findings provide further insight into the evolutionary characteristics of M. catarrhalis." @default.
- W2973702896 created "2019-09-26" @default.
- W2973702896 creator A5009939198 @default.
- W2973702896 creator A5019260361 @default.
- W2973702896 creator A5027836060 @default.
- W2973702896 creator A5039429253 @default.
- W2973702896 creator A5054265107 @default.
- W2973702896 creator A5055204011 @default.
- W2973702896 creator A5074053744 @default.
- W2973702896 creator A5077586446 @default.
- W2973702896 creator A5080782442 @default.
- W2973702896 date "2020-01-01" @default.
- W2973702896 modified "2023-09-25" @default.
- W2973702896 title "Genotypic differences in CC224, CC363, CC449 and CC446 of Moraxella catarrhalis isolates based on whole genome SNP, MLST and PFGE typing" @default.
- W2973702896 cites W1942640082 @default.
- W2973702896 cites W1969557558 @default.
- W2973702896 cites W1972145956 @default.
- W2973702896 cites W1973530626 @default.
- W2973702896 cites W1974858921 @default.
- W2973702896 cites W1980100879 @default.
- W2973702896 cites W1981775484 @default.
- W2973702896 cites W2000859682 @default.
- W2973702896 cites W2034951913 @default.
- W2973702896 cites W2035839217 @default.
- W2973702896 cites W2084303726 @default.
- W2973702896 cites W2089290086 @default.
- W2973702896 cites W2103227153 @default.
- W2973702896 cites W2103441770 @default.
- W2973702896 cites W2108234281 @default.
- W2973702896 cites W2116596529 @default.
- W2973702896 cites W2118299639 @default.
- W2973702896 cites W2119695520 @default.
- W2973702896 cites W2119872996 @default.
- W2973702896 cites W2133059828 @default.
- W2973702896 cites W2152759128 @default.
- W2973702896 cites W2158489424 @default.
- W2973702896 cites W2165155230 @default.
- W2973702896 cites W2284676314 @default.
- W2973702896 cites W2311203695 @default.
- W2973702896 cites W2537144149 @default.
- W2973702896 cites W2756038708 @default.
- W2973702896 cites W2768609411 @default.
- W2973702896 cites W2805371262 @default.
- W2973702896 cites W2883523272 @default.
- W2973702896 doi "https://doi.org/10.1016/j.ijmm.2019.151357" @default.
- W2973702896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31570247" @default.
- W2973702896 hasPublicationYear "2020" @default.
- W2973702896 type Work @default.
- W2973702896 sameAs 2973702896 @default.
- W2973702896 citedByCount "2" @default.
- W2973702896 countsByYear W29737028962022 @default.
- W2973702896 crossrefType "journal-article" @default.
- W2973702896 hasAuthorship W2973702896A5009939198 @default.
- W2973702896 hasAuthorship W2973702896A5019260361 @default.
- W2973702896 hasAuthorship W2973702896A5027836060 @default.
- W2973702896 hasAuthorship W2973702896A5039429253 @default.
- W2973702896 hasAuthorship W2973702896A5054265107 @default.
- W2973702896 hasAuthorship W2973702896A5055204011 @default.
- W2973702896 hasAuthorship W2973702896A5074053744 @default.
- W2973702896 hasAuthorship W2973702896A5077586446 @default.
- W2973702896 hasAuthorship W2973702896A5080782442 @default.
- W2973702896 hasBestOaLocation W29737028961 @default.
- W2973702896 hasConcept C104317684 @default.
- W2973702896 hasConcept C135763542 @default.
- W2973702896 hasConcept C139275648 @default.
- W2973702896 hasConcept C141231307 @default.
- W2973702896 hasConcept C153209595 @default.
- W2973702896 hasConcept C2776551000 @default.
- W2973702896 hasConcept C2776925733 @default.
- W2973702896 hasConcept C2781209916 @default.
- W2973702896 hasConcept C42084846 @default.
- W2973702896 hasConcept C523546767 @default.
- W2973702896 hasConcept C54355233 @default.
- W2973702896 hasConcept C60987743 @default.
- W2973702896 hasConcept C77434933 @default.
- W2973702896 hasConcept C81089528 @default.
- W2973702896 hasConcept C86803240 @default.
- W2973702896 hasConcept C89423630 @default.
- W2973702896 hasConceptScore W2973702896C104317684 @default.
- W2973702896 hasConceptScore W2973702896C135763542 @default.
- W2973702896 hasConceptScore W2973702896C139275648 @default.
- W2973702896 hasConceptScore W2973702896C141231307 @default.
- W2973702896 hasConceptScore W2973702896C153209595 @default.
- W2973702896 hasConceptScore W2973702896C2776551000 @default.
- W2973702896 hasConceptScore W2973702896C2776925733 @default.
- W2973702896 hasConceptScore W2973702896C2781209916 @default.
- W2973702896 hasConceptScore W2973702896C42084846 @default.
- W2973702896 hasConceptScore W2973702896C523546767 @default.
- W2973702896 hasConceptScore W2973702896C54355233 @default.
- W2973702896 hasConceptScore W2973702896C60987743 @default.
- W2973702896 hasConceptScore W2973702896C77434933 @default.
- W2973702896 hasConceptScore W2973702896C81089528 @default.
- W2973702896 hasConceptScore W2973702896C86803240 @default.
- W2973702896 hasConceptScore W2973702896C89423630 @default.
- W2973702896 hasFunder F4320335787 @default.
- W2973702896 hasIssue "1" @default.
- W2973702896 hasLocation W29737028961 @default.
- W2973702896 hasLocation W29737028962 @default.