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• W2973779051 abstract "Systemic inflammation and immune dysfunction have been proved to be significantly associated with cancer progression and metastasis in colorectal cancer (CRC). The aim of this retrospective study was to investigate the association between preoperative systemic immune-inflammation index (SII) and postoperative liver metastasis in CRC.This retrospective study evaluated 182 patients with CRC who underwent surgical resection. The inflammation-based prognostic factors, including SII, neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR) and prognostic nutritional index (PNI), were calculated based on preoperative laboratory data. The univariate and multivariate logistic regression analysis was performed to identify the risk factors correlated with postoperative liver metastasis in CRC. Receiver operating characteristic (ROC) curves and decision curve analysis (DCA) were respectively used to assess the predictive ability and clinical usefulness of SII for postoperative liver metastasis in CRC.The univariate and multivariable analysis confirmed SII was independently correlated with postoperative liver metastasis in CRC (p<0.001), and the ROC and DCA analysis demonstrated SII was superior to other inflammation-based factors in terms of predictive ability.SII is an independent predictive indicator of postoperative liver metastasis for patients with colorectal cancer." @default.
• W2973779051 created "2019-09-26" @default.
• W2973779051 creator A5021925661 @default.
• W2973779051 creator A5058863369 @default.
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• W2973779051 date "2019-09-01" @default.
• W2973779051 modified "2023-10-17" @default.
• W2973779051 title "<p>Predictive Significance Of Preoperative Systemic Immune-Inflammation Index Determination In Postoperative Liver Metastasis Of Colorectal Cancer</p>" @default.
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• W2973779051 doi "https://doi.org/10.2147/ott.s223419" @default.
• W2973779051 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6759789" @default.
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• W2973779051 hasPublicationYear "2019" @default.
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